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Merck

AP503A

Sigma-Aldrich

Goat Anti-Mouse IgG γ chain Antibody, Alkaline Phosphatase conjugate, Species Adsorbed

Chemicon®, from goat

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.46

Biologische Quelle

goat

Qualitätsniveau

Konjugat

alkaline phosphatase conjugate

Antikörperform

affinity purified immunoglobulin

Antikörper-Produkttyp

secondary antibodies

Klon

polyclonal

Speziesreaktivität

mouse

Hersteller/Markenname

Chemicon®

Methode(n)

ELISA: suitable

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Verwandte Kategorien

Allgemeine Beschreibung

IgG is one of the most abundant protein in human serum. IgG is important for our defence against microorganisms and the molecules are produced by B-lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination.

Spezifität

Reacts with heavy chain of mouse IgG1, IgG2a, IgG2b and IgG3. Absorbed for mouse IgM and IgA, pooled human sera and purified human paraproteins. Minimal cross reactivity with human immunoglobulins.
The antibody reacts with the heavy chain of mouse IgG1, IgG2a, IgG2b and IgG3 as demonstrated by ELISA and flow cytometry. Minimal cross reactivity with human immunoglobulins.

Immunogen

Epitope: IgG γ chain
Prepared from purified mouse IgG γ chain. Pooled antisera from goats hyperimmunized with mouse IgG paraproteins.

Anwendung

Research Category
Sekundär- & Kontrollantikörper
Research Sub Category
Sekundärantikörper zur Doppelmarkierung

Fragmentspezifische Sekundärantikörper
ELISA: 1:2,000-1:4,000

Optimal working dilutions must be determined by the end user.
Goat anti-Mouse IgG γ chain Antibody, Alkaline Phosphatase conjugate, Species Adsorbed is an antibody against Mouse IgG γ chain for use in ELISA.

Physikalische Form

Affinity Chromatography
Purified by affinity chromatography on pooled mouse IgG covalently linked to agarose. Liquid in 50mM Tris/1mM MgCl2/50% Glycerol, pH 8.0, containing 0.1% NaN3 as preservative.

Lagerung und Haltbarkeit

Maintain refrigerated at 2°-8°C under sterile conditions for up to twelve months from date of receipt. For long term storage, aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1


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Yoann G Santin et al.
Current biology : CB, 29(21), 3707-3713 (2019-10-22)
The type VI secretion system (T6SS) is a multiprotein apparatus that injects protein effectors into target cells, hence playing a critical role in pathogenesis and in microbial communities [1-4]. The T6SS belongs to the broad family of contractile injection systems

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