ABT189

Anti-Tropomyosin 4 Antibody

from rabbit, purified by affinity chromatography

• Synonym(e): Tropomyosin alpha-4 chain, TM30p1, Tropomyosin-4
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Aufgereinigt durch: affinity chromatography
• Speziesreaktivität: mouse, human, rat
• Speziesreaktivität (Voraussage durch Homologie): bovine (based on 100% sequence homology)
• Methode(n): immunohistochemistry: suitable (paraffin); western blot: suitable
• NCBI-Hinterlegungsnummer: NP_003281
• UniProt-Hinterlegungsnummer: P67936
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... TPM4(7171)

Beschreibung

Allgemeine Beschreibung

Tropomyosin-4 is also called Tropomyosin alpha-4 chain and TM30p1. Tropomyosin-4 binds calcium and to actin filaments in muscle and non-muscle cells. Tropomyosin-4 associates with the troponin complex, and plays a role in the regulation of smooth and striated muscle contraction, as well as the stabilization of cytoskeleton actin filaments in non-muscle cells. Tropomyosin-4 is found in cardiac tissue and platelets.

Spezifität

This antibody recognizes the C-terminus of Tropomyosin 4.

Immunogen

KLH-conjugated linear peptide corresponding to the C-terminus of human Tropomyosin 4.

Anwendung

Anti-Tropomyosin 4 Antibody is an antibody against Tropomyosin 4 for use in western blotting & IHC (Paraffin).

Immunohistochemistry Analysis: A 1:100 dilution from a representative lot detected Tropomyosin 4 in human prostate cancer sections and human heart sections tissue.

Qualität

Evaluated by Western Blotting in NIH/3T3 cell lysate.

Western Blotting Analysis: A 1:2,500 dilution of this antibody detected Tropomyosin 4 in 10 µg of NIH/3T3 cell lysate.

Zielbeschreibung

~33 kDa observed. The calculated molecular weight is 29 kDa, however Tropomyosin 4 has been shown as a ~33 kDa band in western blots (Brooke, K., et al. (2006). Bone. 39:697-705).

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable