ABN462
Anti-Dopamine D2 Receptor Antibody
from rabbit, purified by affinity chromatography
Synonym(e):
Dopamine D2 Receptor, D2R
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About This Item
UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Empfohlene Produkte
Biologische Quelle
rabbit
Qualitätsniveau
Antikörperform
affinity isolated antibody
Antikörper-Produkttyp
primary antibodies
Klon
polyclonal
Aufgereinigt durch
affinity chromatography
Speziesreaktivität
mouse
Methode(n)
immunohistochemistry: suitable
NCBI-Hinterlegungsnummer
UniProt-Hinterlegungsnummer
Versandbedingung
wet ice
Posttranslationale Modifikation Target
unmodified
Angaben zum Gen
mouse ... Drd2(13489)
Allgemeine Beschreibung
The Dopamine D2 Receptor is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. 2 isoforms are reported for the D2 Dopamine Receptor, Isoform 1 and isoform 2 which are expressed in the pituitary and brain; Isoform 1 is expressed seven times more than isoform 2 in the caudate nucleus.
Spezifität
This antibody binds to the cytoplasmic third intracellular loop.
Immunogen
Epitope: cytoplasmic third intracellular loop
Recombinant protein corresponding to the cytoplasmic domain of mouse Dopamine D2 Receptor.
Anwendung
Research Category
Neurowissenschaft
Neurowissenschaft
Research Sub Category
Entwicklungsabhängige Signalübertragung
Entwicklungsabhängige Signalübertragung
Anti-Dopamine D2 Receptor Antibody is an antibody against Dopamine D2 Receptor for use in Immunohistochemistry.
Immunohistochemistry Analysis: A representative lot detected Dopamine D2 Receptor in WT mouse striatum tissue (Trifilieff, P., et al. (2013). Molecular Psychiatry. 18:102-1033).
Immunohistochemistry Analysis: A representative lot detected Dopamine D2 Receptor in wild-type and not in D2R knockout mouse sriatum tissue (Trifilieff, P., et al. (2011). BioTechniques. 50:111-118).
Immunohistochemistry Analysis: A representative lot detected Dopamine D2 Receptor in wild-type and not in D2R knockout mouse sriatum tissue (Trifilieff, P., et al. (2011). BioTechniques. 50:111-118).
Qualität
Evaluated by Immunohistochemistry in mouse striatum tissue.
Immunohistochemistry Analysis: A 1:250 dilution of this antibody detected Dopamine D2 Receptor in mouse striatum tissue.
Immunohistochemistry Analysis: A 1:250 dilution of this antibody detected Dopamine D2 Receptor in mouse striatum tissue.
Zielbeschreibung
50.9 kDa calculated
Physikalische Form
Affinity
Purified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide.
Lagerung und Haltbarkeit
Stable for 1 year at 2-8°C from date of receipt.
Sonstige Hinweise
Concentration: Please refer to lot specific datasheet.
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Lagerklassenschlüssel
12 - Non Combustible Liquids
WGK
WGK 2
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.
Jérôme Jeanblanc et al.
Brain : a journal of neurology (2024-05-05)
The use of psilocybin to treat alcohol use disorder is very promising, but the mechanisms of action remain poorly understood. We combined behavioral, pharmacological and gene expression analyses to decipher the mechanisms of action of psilocybin, for the first time
Ying Zhu et al.
BioTechniques, 68(3), 122-129 (2019-12-21)
Despite the controversy regarding the existence and physiological relevance of class A G protein-coupled receptor dimerization, there is substantial evidence for functional interactions between the dopamine D2 receptor (D2R) and the adenosine A2A receptor (A2AR). A2AR-D2R complexes have been detected in
Andry Andrianarivelo et al.
Science advances, 7(43), eabg5970-eabg5970 (2021-10-21)
[Figure: see text].
Benjamin Lassus et al.
Scientific reports, 8(1), 17461-17461 (2018-12-01)
Although the prefrontal cortex and basal ganglia are functionally interconnected by parallel loops, cellular substrates underlying their interaction remain poorly understood. One novel approach for addressing this issue is microfluidics, a methodology which recapitulates several intrinsic and synaptic properties of
Ying Zhu et al.
Current protocols in neuroscience, 91(1), e86-e86 (2020-01-17)
Combining immunological and molecular biological methods, the antibody-based proximity ligation assay (PLA) has been used for more than a decade to detect and quantify protein-protein interactions, protein modification, and protein expression in situ, including in brain tissue. However, the transfer
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