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AB10618

Sigma-Aldrich

Anti-BAL Antibody

Chemicon®, from rabbit

Synonym(e):

B-aggressive lymphoma

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Speziesreaktivität

human

Hersteller/Markenname

Chemicon®

Methode(n)

immunoprecipitation (IP): suitable
western blot: suitable

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... PARP9(83666)

Allgemeine Beschreibung

BAL (B-aggressive lymphoma) is a novel risk-related gene that is expressed at significantly higher levels in fatal high-risk diffuse large B-cell lymphomas (DLB-CL) than in cured low-risk tumors. The major BAL cDNA encodes a 88 kDa nuclear protein. BAL-overexpressing B-cell lymphoma transfectants have significantly higher rates of migration than vector-only transfectants, indicating that the risk-related BAL gene promotes malignant B-cell migration.

Spezifität

Reactivity has been confirmed in with human Farage non-Hodgkin′s B-cell lymphoma and human BC-1 B-lymphocyte lymphoma lysates.
Recognizes BAL.

Immunogen

Synthetic peptide derived from the C-terminal region of the short isoform of human BAL protein (B-aggressive lymphoma, poly (ADP-ribose) polymerase family member 9, PARP9).

Anwendung

Research Category
Apoptose & Krebs

Epigenetik & nukleäre Funktionen
Research Sub Category
Tumormarker

Transkriptionsfaktoren
Anti-BAL Antibody is an antibody against BAL for use in IP & WB.
Western blotting: 1-3 μg/mL
Immunoprecipitation: 7 μg/ reaction

Physikalische Form

ImmunoAffinity Purified
Format: Purified
This polyclonal antibody is supplied in 400 μL of phosphate buffered saline (pH 7.4) containing 0.1% sodium azide.

Lagerung und Haltbarkeit

Store at -20°C in undiluted aliquots for 1 year from date of shipment.

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Junji Xing et al.
Nature communications, 12(1), 2681-2681 (2021-05-13)
Innate immune cells are critical in protective immunity against viral infections, involved in sensing foreign viral nucleic acids. Here we report that the poly(ADP-ribose) polymerase 9 (PARP9), a member of PARP family, serves as a non-canonical sensor for RNA virus
Samia B Bachmann et al.
Molecular cancer, 13, 125-125 (2014-06-03)
Prostate cancer (PCa) is one of the leading causes of cancer-related mortality and morbidity in the aging male population and represents the most frequently diagnosed malignancy in men around the world. The Deltex (DTX)-3-like E3 ubiquitin ligase (DTX3L), also known

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