420123-M

JNK Inhibitor II, Negative Control

The JNK Inhibitor II, Negative Control, also referenced under CAS 54642-23-8, controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

• Synonym(e): JNK Inhibitor II, Negative Control, N¹-Methyl-1,9-pyrazoloanthrone
• Empirische Formel (Hill-System): C₁₅H₁₀N₂O
• CAS-Nummer: 54642-23-8
• Molekulargewicht: 234.25
• UNSPSC-Code: 12352200

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥97% (HPLC)
• Form: solid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; protect from light
• Farbe: yellow
• Löslichkeit: DMSO: 10 mg/mL
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

A useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119). Inhibits JNK2 and JNK3 only at much higher concentrations (IC₅₀ = 18 µM and 24 µM, respectively) compared to SP600125 (IC₅₀ = 40 nM and 90 nM, respectively).

A useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119). Inhibits JNK2 and JNK3 only at much higher concentrations (IC₅₀ = 18 µM and 24 µM, respectively) compared to SP600125 (IC₅₀ = 40 nM and 90 nM, respectively).

Biochem./physiol. Wirkung

Primary Target
A useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119)

Target IC₅₀: 18 µM and 24 µM against JNK2 and JNK3, respectively

Warnhinweis

Toxicity: Standard Handling (A)

Rekonstituierung

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable up to 3 months at -20°C.

Sonstige Hinweise

Shin, M., and Boyd, Y.D. 2002. Biochim. Biophys. Acta1589, 311.
Bennett, B.L., et al. 2001. Proc. Natl. Acad. Sci. USA98, 13681.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable