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Furosemide Impurity Mixture solution

5 μg/mL (50:50 Acetonitrile:Water, each analyte), certified reference material, ampule of 1 mL, Cerilliant®

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About This Item

Empirische Formel (Hill-System):
C12H11ClN2O5S
Molekulargewicht:
330.74
UNSPSC-Code:
12352200
NACRES:
NA.24

Qualität

certified reference material

Form

liquid

Leistungsmerkmale

Snap-N-Spike®/Snap-N-Shoot®

Zusammensetzung

2-Chloro-4-furfurylamino-5-sulfamoylbenzoic acid, 5 μg/mL
4-Chloro-5-sulfamoylanthranilic acid (Furosemide RCB), 5 μg/mL
Furosemide, 5 μg/mL

Verpackung

ampule of 1 mL

Hersteller/Markenname

Cerilliant®

Konzentration

5 μg/mL (50:50 Acetonitrile:Water, each analyte)

Methode(n)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Anwendung(en)

pharmaceutical (small molecule)

Format

multi-component solution

Lagertemp.

−20°C

Allgemeine Beschreibung

Furosemide is a powerful diuretic agent with the ascending limb of Henle′s loop of nephron as its primary site of action. It works by preventing the reabsorption of sodium and increasing the secretion of renal vasodilatory prostaglandin E. In combination with nitrates, it is used as the standard treatment for pulmonary edema caused by acute heart failure.

Anwendung

Furosemide Impurity Mixture solution may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Rechtliche Hinweise

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Analyt

Beschreibung
    Furosemide, Pharmaceutical Secondary Standard; Certified Reference Material
    Furosemide Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material
    Furosemide Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

Piktogramme

FlameExclamation mark
GHS02,GHS07

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 2

Flammpunkt (°F)

50.0 °F

Flammpunkt (°C)

10 °C

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Furosemide effect on isolated perfused tubules
Burg M, et al.
The American Journal of Physiology, 225(1), 119-124 (1973)
Lack of renoprotective effects of dopamine and furosemide during cardiac surgery
Lassnigg A, et al.
Journal of the American Society of Nephrology, 11(1), 97-104 (2000)
Randomised trial of high-dose isosorbide dinitrate plus low-dose furosemide versus high-dose furosemide plus low-dose isosorbide dinitrate in severe pulmonary oedema
Cotter G, et al.
Lancet, 351(9100), 389-393 (1998)
Furosemide
USP42/NF37: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 41(3), 2006-2006 (2018)

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