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C-006

Supelco

Kodein -Lösung

1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirische Formel (Hill-System):
C18H21NO3
CAS-Nummer:
76-57-3
Molekulargewicht:
299.36
EG-Nummer:
200-659-6
UNSPSC-Code:
41116107
NACRES:
NA.24

Qualität

certified reference material

Form

liquid

Leistungsmerkmale

SNAP-N-SPIKE®, SNAP-N-SHOOT®

Verpackung

ampule of 1 mL

Hersteller/Markenname

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

Konzentration

1 mg/mL in methanol

Methode(n)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Anwendung(en)

forensics and toxicology

Format

single component solution

Lagertemp.

−20°C

SMILES String

COc1ccc2C[C@@H]3[C@@H]4C=C[C@H](O)[C@@H]5Oc1c2[C@]45CCN3C

InChI

1S/C18H21NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3-6,11-13,17,20H,7-9H2,1-2H3/t11-,12+,13-,17-,18-/m0/s1

InChIKey

OROGSEYTTFOCAN-DNJOTXNNSA-N

Angaben zum Gen

human ... OPRD1(4985) , OPRK1(4986) , OPRM1(4988)

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Verwandte Kategorien

Allgemeine Beschreibung

Codeine is an opiate used for its analgesic, antitussive, and sedative properties and is the second-most predominant alkaloid in opium. This certified reference solution is suitable for use as a starting material in calibrators and controls for LC/MS and GC/MS testing methods in clinical toxicology, forensic analysis, pharmaceutical research, and pain prescription monitoring. As a widely popular recreational drug, codeine is regulated under various narcotic control laws in countries such as Australia, New Zealand, Romania, Sweden, and the United States. Since opiates are classified as controlled substances, Cerilliant offers most opiate reference standards as DEA-exempt solutions for added convenience.

Anwendung


  • Codeine Solution in Opioid Receptor Studies: A recent review discusses the phytochemical and nutritional composition of Papaver plants, known for containing codeine. It outlines the plant′s biotechnological applications, potentially relevant for opioid receptor studies, and can be a basis for developing high-purity codeine solutions for research purposes. This highlights codeine′s role in biochemical research, especially in studying analgesic mechanisms and opioid receptor pharmacology (Butnariu et al., 2022).

Rechtliche Hinweise

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Zielorgane

Eyes,Central nervous system

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 2

Flammpunkt (°F)

51.8 °F - closed cup

Flammpunkt (°C)

11.0 °C - closed cup

Analysenzertifikate (COA)

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We investigated whether morphine and its pro-drug codeine are substrates of the highly genetically polymorphic organic cation transporter OCT1 and whether OCT1 polymorphisms may affect morphine and codeine pharmacokinetics in humans. Morphine showed low transporter-independent membrane permeability (0.5 × 10⁻⁶
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