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LM2001

Avanti

Sphinganine (d17:0)

heptadecasphinganine, ethanol solution

Synonym(e):

(2S,3R)-2-aminoheptadecane-1,3-diol, C17 Sphinganine

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About This Item

Empirische Formel (Hill-System):
C17H37NO2
CAS-Nummer:
32164-02-6
Molekulargewicht:
287.48
UNSPSC-Code:
12352211
NACRES:
NA.25

Form

ethanol solution

Verpackung

pkg of 1 × 1 mL (LM2001-1EA)

Hersteller/Markenname

Avanti Research™ - A Croda Brand LM2001

Konzentration

~10 μg/mL (Refer to C of A for lot specific concentration.)

Versandbedingung

dry ice

Lagertemp.

−20°C

SMILES String

OC[C@@](N)([H])[C@]([H])(O)CCCCCCCCCCCCCC

InChI

1S/C17H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(20)16(18)15-19/h16-17,19-20H,2-15,18H2,1H3/t16-,17+/m0/s1

InChIKey

KFQUQCFJDMSIJF-DLBZAZTESA-N

Allgemeine Beschreibung

Sphinganine, also known as dihydrosphingosine is a sphingoid base precursor of ceramide.

Anwendung

Sphinganine (d17:0) has been used as a constituent of the internal standard mixture in mass spectrometry.

Biochem./physiol. Wirkung

Sphinganine (SPA) is involved in sphingolipid biosynthesis pathway. It is free from the double bond. SPA has an ability to inhibit the activity of protein kinase c. SPA accumulation enables fumonisin B1 to stimulate apoptosis.
Sphinganine plays a vital role in cell regulation, cell growth modulation and signal transmission, functioning as an inhibitor of protein kinase C. It inhibits the low-density lipoprotein-induced esterification of cholesterol by the blockage of post-lysosomal cholesterol transport. Sphinganine is useful as a biomarker for studying microbial diversity.

Verpackung

2 mL Amber Glass Sealed Ampule (LM2001-1EA)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Piktogramme

FlameExclamation mark
GHS02,GHS07

Signalwort

Danger

H-Sätze

H225,H319

Gefahreneinstufungen

Eye Irrit. 2 - Flam. Liq. 2

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 1

Flammpunkt (°F)

55.4 °F - closed cup

Flammpunkt (°C)

13.0 °C - closed cup

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Analysenzertifikate (COA)

Lot/Batch Number

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Die Dokumentenbibliothek aufrufen

Urinary metabolomic profiling in Zucker diabetic fatty rats with type 2 diabetes mellitus treated with glimepiride, metformin, and their combination
Dong Y, et al.
Molecules (Basel), 21(11), 1446-1446 (2016)
A stereoselective synthesis of dihydrosphingosine
Fernandes RA and Kumar P
European Journal of Organic Chemistry, 2000(20), 3447-3449 (2000)
Persistence and reversibility of the elevation in free sphingoid bases induced by fumonisin inhibition of ceramide synthase
Enongene EN, et al.
Toxicological Sciences, 67(2), 173-181 (2002)
Quantification of sphingosine and sphinganine from crude lipid extracts by HPLC electrospray ionization tandem mass spectrometry
Lieser B, et al.
Journal of Lipid Research, 44(11), 2209-2216 (2003)
Estradiol induces export of sphingosine 1-phosphate from breast cancer cells via ABCC1 and ABCG2
Takabe, et al.
Test, 285(14) (2010)
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