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Sigma-Aldrich

Polyester bis-MPA dendron

carboxyl, 1 biotin (core), generation 2, no. Surface Groups 4

Synonym(e):

Bis-MPA dendron, PFd-G1-Biotin-COOH

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About This Item

Empirische Formel (Hill-System):
C49H72N2O28S
Molekulargewicht:
1169.16
UNSPSC-Code:
12162002
NACRES:
NA.23

Form

solid

Mol-Gew.

generation 2

Anzahl Oberflächengruppen

4

Farbe

colorless to white

Lagertemp.

−20°C

Allgemeine Beschreibung

  • Polymer architecture: Dendron
  • Generation: 2
  • Core functional group: Biotin
  • End Group Functionality: Carboxylic acid
  • No. Surface Groups: 4
  • Calculated Mol. Wt.: 1169.16 g/mol
  • Bis-MPA = 2,2-Bis(hydroxymethyl)propionic acid

Anwendung

Bis-MPA dendritic molecules are based on 2,2-bismethylolpropionicacid (bis-MPA) building blocks. The hydrolysable linkers presented in this type of polymers allows their degradation into byproducts that can be reabsorbed by the body or into excretable non-toxic small molecules. Therefore, this group of dendritic polymers are biocompatible and biodegradable, making them suitable for biomedical applications. The carboxylic acid-functionalized corona and biotin-functionalized core of this product can be readily used in bioconjugation reactions.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications.
Garcia-Gallego S, et al.
Progress in Polymer Science, 48, 85-110 (2015)
Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications.
Garcia-Gallego S, et al
Progress in Polymer Science, 48, 85-110 (2015)
Anna Carlmark et al.
Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)
Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been

Artikel

Dendritic Polyester Scaffolds for Drug Delivery

Dendritic molecules' biomedical applications, particularly bis-MPA dendritic scaffolds, hold promise for drug delivery.

New Multi-Dendrimer Platforms for Supramolecular Assembly

Dendrimers, polymer nanostructures, are synthesized for specific purposes by manipulating critical nanoscale design parameters (CNDPs).

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