901575

t-Boc-N-amido-PEG₃-CH₂CO₂H

≥95%

• Empirische Formel (Hill-System): C₁₃H₂₅NO₇
• CAS-Nummer: 462100-06-7
• Molekulargewicht: 307.34
• MDL-Nummer: MFCD22376773
• UNSPSC-Code: 51171641
• NACRES: NA.22

Eigenschaften

• Assay: ≥95%
• Form: liquid
• Eignung der Reaktion: reagent type: linker
• Funktionelle Gruppe: Boc; amine; carboxylic acid
• Lagertemp.: −20°C
• SMILES String: OC(COCCOCCOCCNC(OC(C)(C)C)=O)=O
• InChI: 1S/C13H25NO7/c1-13(2,3)21-12(17)10(14)8-19-6-4-18-5-7-20-9-11(15)16/h10H,4-9,14H2,1-3H3,(H,15,16)
• InChIKey: FUUVHHQEYXVKFA-UHFFFAOYSA-N

Beschreibung

Anwendung

This is a crosslinker with a t-Boc protected amine on one end and a carboxyl group on the other end. The compound contains three PEG units to help improve solubility.

t-Boc-N-amido-PEG₃-CH₂CO₂H is a heterobifunctional, PEGylated crosslinker featuring a Boc-protected amine at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. t-Boc-N-amido-PEG₃-CH₂CO₂H can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC^® molecules) for targeted protein degradation.

Rechtliche Hinweise

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3