900914

Methyltetrazine-NHS ester

≥95%

• Synonym(e): 2,5-Dioxo-1-pyrrolidinyl 4-(6-methyl-1,2,4,5-tetrazin-3-yl)benzeneacetate
• Empirische Formel (Hill-System): C₁₅H₁₃N₅O₄
• CAS-Nummer: 1644644-96-1
• Molekulargewicht: 327.29
• MDL-Nummer: MFCD28334557
• UNSPSC-Code: 12352108
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥95%
• Form: powder or crystals
• Eignung der Reaktion: reaction type: click chemistry; reagent type: cross-linking reagent
• Funktionelle Gruppe: NHS ester
• Lagertemp.: −20°C
• SMILES String: O=C(ON1C(CCC1=O)=O)CC(C=C2)=CC=C2C3=NN=C(C)N=N3

Beschreibung

Anwendung

Methyltetrazine-NHS ester has an N-hydroxysuccinimide (NHS) ester that can be reacted with primary amines and a methyltetrazine, which is reactive to trans-cyclooctenes. The NHS ester reacts with primary amines (e.g. side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic pH to form covalent bonds. The short spacer arm adds minimal mass to modified molecules (230.2 daltons). It is generally used in click chemistry applications in bioconjugate chemistry.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable