83060

12-Amino-4,7,10-trioxadodecansäure-tert.-butylester

technical, ≥80% (T)

• Synonym(e): 3-[2-(2-(2-Aminoethoxy)-ethoxy)-ethoxy]-propionsäure-tert.-butylester
• Empirische Formel (Hill-System): C₁₃H₂₇NO₅
• CAS-Nummer: 252881-74-6
• Molekulargewicht: 277.36
• MDL-Nummer: MFCD06201017
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 57652942
• NACRES: NA.22

Eigenschaften

• Qualität: technical
• Assay: ≥80% (T)
• Form: solid
• Eignung der Reaktion: reagent type: cross-linking reagent
• Lagertemp.: −20°C
• SMILES String: CC(C)(C)OC(=O)CCOCCOCCOCCN
• InChI: 1S/C13H27NO5/c1-13(2,3)19-12(15)4-6-16-8-10-18-11-9-17-7-5-14/h4-11,14H2,1-3H3
• InChIKey: CWFSAZJIJBTKRC-UHFFFAOYSA-N

Beschreibung

Anwendung

tert-Butyl 12-amino-4,7,10-trioxadodecanoate is generally used as a spacer or linker in bioconjugate chemistry. Some of its applications are:

• Synthesis of the tetanus-toxin conjugate of MUC1 glycopeptide antigen, as a potential antitumor vaccine.
• Synthesis of self-assembled monolayer-based surface-enhanced raman scattering (SERS) labels for immuno-SERS microscopy.
• Synthesis of polycationic adamantane-based dendrons for cell imaging.
• Synthesis of phthalocyanine (Pc)-peptide conjugates as potential fluorescence imaging agents for cancers overexpressing epidermal growth factor receptors (EGFR).

Sonstige Hinweise

Intermediate in the synthesis of a spacer for combinatorial chemistry

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): 337.5 °F
• Flammpunkt (°C): 169.7 °C
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type ABEK (EN14387) respirator filter