657123

4-Amino-3-Jodbenzonitril

98%

• Synonym(e): 4-Cyan-2-iodanilin
• Lineare Formel: IC₆H₃(NH₂)CN
• CAS-Nummer: 33348-34-4
• Molekulargewicht: 244.03
• MDL-Nummer: MFCD04039964
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24884265
• NACRES: NA.22

Eigenschaften

• Assay: 98%
• mp (Schmelzpunkt): 112-115 °C (lit.)
• SMILES String: Nc1ccc(cc1I)C#N
• InChI: 1S/C7H5IN2/c8-6-3-5(4-9)1-2-7(6)10/h1-3H,10H2
• InChIKey: UOWVTQFTEAYDLM-UHFFFAOYSA-N

Beschreibung

Anwendung

Reactant involved in:

• Hydroamination-double hydroarylation for synthesis of fuzed carbazoles
• Cycloisomerizations of aromatic homo- and bis-homopropargylic amine / amide intermediates
• Asymmetric organocatalytic condensation and cycloaddition
• Regioselective aryl C-H bond functionalization
• Synthesis of [(triisopropylsilyl)ethynyl]indole derivatives
• Domino condensation / S-arylation / heterocyclization reactions

Palladium-catalyzed carbonylation of iodoanilines provides ketoamides in the presence of primary and secondary amines.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves