642002

(3S,5R,8aS)-(+)-Hexahydro-3-phenyl-5H-oxazolo[3,2-a]pyridin-5-carbonitril

97%

• Synonym(e): (+)-2-Cyan-6-phenyloxazolopiperidin, [3S-(3α,5β,8ab)]-Hexahydro-3-phenyl-5-H-oxazolo[3,2-a]pyridin-5-carbonitril
• Empirische Formel (Hill-System): C₁₄H₁₆N₂O
• CAS-Nummer: 106565-71-3
• Molekulargewicht: 228.29
• MDL-Nummer: MFCD08276761
• UNSPSC-Code: 12352005
• PubChem Substanz-ID: 24883163
• NACRES: NA.22

Eigenschaften

• Assay: 97%
• Form: solid
• mp (Schmelzpunkt): 79-83 °C (lit.)
• SMILES String: [H][C@]12CCC[C@H](C#N)N1[C@H](CO2)c3ccccc3
• InChI: 1S/C14H16N2O/c15-9-12-7-4-8-14-16(12)13(10-17-14)11-5-2-1-3-6-11/h1-3,5-6,12-14H,4,7-8,10H2/t12-,13-,14+/m1/s1
• InChIKey: GQHMNZGZXHZLEN-MCIONIFRSA-N

Beschreibung

Anwendung

(3S,5R,8aS)-(+)-Hexahydro-3-phenyl-5H-oxazolo[3,2-a]pyridine-5-carbonitrile can be used as a starting material:

• To prepare spirocyclic aminochroman derivatives as possible 5-HT_1A agonists.
• In the asymmetric synthesis of aza-analogs of podophyllotoxin as potent antitumor agents.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302
• Gefahreneinstufungen: Acute Tox. 4 Oral
• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Faceshields, Gloves