592293

Chlorameisensäure-2-methoxyethylester

• Synonym(e): (2-Methoxyethoxy)-carbonylchlorid, Chlor-(2-methoxyethoxy)-methanone
• Lineare Formel: CH₃OCH₂CH₂OCOCl
• CAS-Nummer: 628-12-6
• Molekulargewicht: 138.55
• EG-Nummer: 211-026-9
• MDL-Nummer: MFCD00058932
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24881382

Eigenschaften

• Brechungsindex: n20/D 1.4200 (lit.)
• bp: 157-158 °C (lit.)
• Dichte: 1.192 g/mL at 25 °C (lit.)
• Lagertemp.: 2-8°C
• SMILES String: COCCOC(Cl)=O
• InChI: 1S/C4H7ClO3/c1-7-2-3-8-4(5)6/h2-3H2,1H3
• InChIKey: NDYYWMXJZWHRLZ-UHFFFAOYSA-N

Beschreibung

Anwendung

Reactant for:

• Preparation of N-bridged bicyclic sulfonamides as inhibitors of γ-secretase
• Preparation of dimethoxyethyl azodicarboxylate via amidation/oxidation and application to Mitsunobu reaction
• Regioselective, stereoselective, and kinetically-controlled nickel-catalyzed cyanoesterification of allenes chloroformates and TMSCN
• Preparation of amino carboxamidobenzothiazoles as Lck inhibitors
• Preparation of nonracemic spirooxindoles using a stereoselective three-component coupling reaction as the key step and using acylation reactions to add structural diversity

Sicherheitshinweise

• Piktogramme: GHS02,GHS05
• Signalwort: Danger
• H-Sätze: H226,H314
• P-Sätze: P210 - P233 - P240 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): 138.0 °F - closed cup
• Flammpunkt (°C): 58.9 °C - closed cup
• Persönliche Schutzausrüstung: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter