512753

2-Chlor-6-methoxyphenylborsäure

≥95%

• Synonym(e): 2-Chloro-6-methoxybenzeneboronic acid, 6-Chloro-2-methoxyphenylboronic acid
• Lineare Formel: ClC₆H₃(OCH₃)B(OH)₂
• CAS-Nummer: 385370-80-9
• Molekulargewicht: 186.40
• MDL-Nummer: MFCD04039878
• UNSPSC-Code: 12352103
• PubChem Substanz-ID: 24873654
• NACRES: NA.22

Eigenschaften

• Assay: ≥95%
• mp (Schmelzpunkt): 162-165 °C (lit.)
• Funktionelle Gruppe: chloro
• SMILES String: COc1cccc(Cl)c1B(O)O
• InChI: 1S/C7H8BClO3/c1-12-6-4-2-3-5(9)7(6)8(10)11/h2-4,10-11H,1H3
• InChIKey: XNWCIDBPLDKKAG-UHFFFAOYSA-N

Beschreibung

Anwendung

2-Chloro-6-methoxyphenylboronic acid can be used as a reactant:

• In the palladium-catalyzed Suzuki-Miyaura coupling reaction.
• To synthesize canthin-6-one alkaloids by reacting with 8-bromo-1,5-naphthyridin-2-one via Pd-catalyzed Suzuki coupling and Cu-catalyzed amidation reactions.
• To prepare tryptamines via Suzuki coupling of vinylsulfonylmethyl resin-bound bromotryptamine.

Reactant for:

• Suzuki coupling
• Preparation of inhibitors of cholesteryl ester transfer protein to raise HDLc levels
• Pd-catalyzed Suzuki-Miyaura coupling
• Solid-phase synthesis of 2,3,5-trisubstituted indoles

Sonstige Hinweise

Contains varying amounts of anhydride

Sicherheitshinweise

• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)