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Sigma-Aldrich

o-Fluor-L-phenylalanin

puriss., ≥99.0% (sum of enantiomers, HPLC)

Synonym(e):

2-Fluor-L-phenylalanin

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About This Item

Empirische Formel (Hill-System):
C9H10FNO2
CAS-Nummer:
19883-78-4
Molekulargewicht:
183.18
Beilstein:
2805791
MDL-Nummer:
MFCD00066448
UNSPSC-Code:
12352200
PubChem Substanz-ID:
24870852

Qualität

puriss.

Assay

≥99.0% (sum of enantiomers, HPLC)

Optische Aktivität

[α]20/D −14±1°, c = 1% in H2O

Optische Reinheit

enantiomeric ratio: ≥99.5:0.5 (TLC)

SMILES String

N[C@@H](Cc1ccccc1F)C(O)=O

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

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Kensuke Okuda et al.
Biochemistry, 44(17), 6675-6684 (2005-04-27)
The ribosome-catalyzed peptidyl transferase reaction displays a complex pH profile resulting from two functional groups whose deprotonation is important for the reaction, one within the A-site substrate and a second unidentified group thought to reside in the rRNA peptidyl transferase
K Kubota et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 37(2), 320-325 (1996-02-01)
L-[methyl-11C]methionine (11C-Met) is a useful tracer for tumor imaging with PET. The drawbacks include a short half-life and high physiological accumulation in abdominal organs. To overcome these shortfalls, the feasible use of [18F]fluorophenylalanine (18F-Phe), which shares the same amino acid
Johnny Castillo Meleán et al.
Organic & biomolecular chemistry, 9(3), 765-769 (2010-11-23)
2-[(18)F]Fluoro-L-phenylalanine and 2-[(18)F]fluoro-L-tyrosine have been developed as promising radiopharmaceuticals for molecular imaging using positron emission tomography (PET). However, the lack of a convenient radiosynthetic pathway has limited their practical use. In this work a new three-step nucleophilic synthesis of these
H Ito et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 36(7), 1232-1237 (1995-07-01)
Neutral amino acids (NAAs) are transported from the blood to the brain using the same carrier system in a competitive fashion. The purpose of this study is to establish a method for evaluating neutral amino acid transport at the blood-brain
J Hatazawa et al.
Annals of nuclear medicine, 8(3), 213-217 (1994-08-01)
We studied the brain uptake of amino acid in a patient with acute cerebral infarction with L-[2-(F-18)]fluorophenylalanine and positron emission tomography. The increased accumulation of the ligand was specifically found in the peri-infarct area where oxygen metabolism was still maintained
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