391468

4-Hydroxypiperidin -hydrochlorid

98%

• Synonym(e): 4-Piperidinol -hydrochlorid
• Empirische Formel (Hill-System): C₅H₁₁NO · HCl
• CAS-Nummer: 5382-17-2
• Molekulargewicht: 137.61
• Beilstein: 3908995
• EG-Nummer: 226-374-7
• MDL-Nummer: MFCD00035298
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24864381
• NACRES: NA.22

Eigenschaften

• Assay: 98%
• mp (Schmelzpunkt): 155-157 °C (lit.)
• Löslichkeit: methanol: soluble 25 mg/mL, clear, colorless
• Funktionelle Gruppe: hydroxyl
• SMILES String: Cl[H].OC1CCNCC1
• InChI: 1S/C5H11NO.ClH/c7-5-1-3-6-4-2-5;/h5-7H,1-4H2;1H
• InChIKey: VKCORPXOKYDINR-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

4-Hydroxypiperidine hydrochloride is a piperidine derivative. The synthesis of 4-hydroxypiperidine has been reported. 4-Hydroxypiperidine participates in the synthesis of 4-(4′-hydroxypiperidino)-4-phenylcyclohexanol and 1-(4-hydroxypiperidino)cyclohexanecarbonitrile. 4-Hydroxypiperidine is the starting material for the synthesis of Sibrafiban and Lamifiban, two non-peptidefibrinogen receptor.

Anwendung

4-Hydroxypiperidine hydrochloride is suitable for use in the Ugi-multi component reaction (MCR) to study the use of miniaturised-synthesis and Total Analysis System (mSYNTAS) in solution phase synthesis and on-line analysis of Ugi-MCRs. It may be used in the synthesis of acetic acid-piperidine-4-yl ester.

Reactant for synthesis of:
14C-labeled E4010
PET tracer for imaging brain acetylcholinesterase

Reactant for allosteric modulators of metabotropic glutamate receptor subtype 5

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves