274259

Methyl-P,P-bis(2,2,2-trifluorethyl)phosphonacetat

95%

• Synonym(e): Bis-(2,2,2-trifluorethyl)-phosphonoessigsäure-methylester
• Lineare Formel: CH₃O₂CCH₂P(O)(OCH₂CF₃)₂
• CAS-Nummer: 88738-78-7
• Molekulargewicht: 318.11
• Beilstein: 3594044
• MDL-Nummer: MFCD00009901
• UNSPSC-Code: 12352108
• PubChem Substanz-ID: 24856576
• NACRES: NA.22

Eigenschaften

• Assay: 95%
• Form: liquid
• Eignung der Reaktion: reaction type: C-C Bond Formation
• Brechungsindex: n20/D 1.370 (lit.)
• Dichte: 1.504 g/mL at 25 °C (lit.)
• SMILES String: COC(=O)CP(=O)(OCC(F)(F)F)OCC(F)(F)F
• InChI: 1S/C7H9F6O5P/c1-16-5(14)2-19(15,17-3-6(8,9)10)18-4-7(11,12)13/h2-4H2,1H3
• InChIKey: PVSJXEDBEXYLML-UHFFFAOYSA-N

Beschreibung

Anwendung

Methyl P,P-bis(2,2,2-trifluoroethyl)phosphonoacetate can be used:

• In one of the key synthetic steps for the preparation of trans-hydrindanes and (R)-(+)-umbelactone.
• To prepare a cis-olefinic ester derivative by Still–Gennari olefination of an aldehyde derivative using 18-crown ether and potassium bis(trimethylsilyl)amide (KHMDS).
• In the synthesis of (−)-(6S,2′S)-epi cryptocaryalactone.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): 230.0 °F - closed cup
• Flammpunkt (°C): 110 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type ABEK (EN14387) respirator filter