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FLT1

fms-related tyrosine kinase 1

Synonyme:
FLT, FLT-1, VEGFR-1, VEGFR1
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(2321) Summary: This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009]
  • Mouse(14254) FMS-like tyrosine kinase 1
  • Rat(54251) FMS-related tyrosine kinase 1
  • domestic guinea pig(100732326) fms-related tyrosine kinase 1
  • Zebrafish(544667) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • dog(403727) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • domestic cat(101088292) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • sheep(443088) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • chicken(374100) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • Horse(100061940) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • cow(503620) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • Domestic Rabbit(100343352) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • Horse(100033957) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • naked mole-rat(101711333) fms-related tyrosine kinase 1

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ELISA

Produktnummer
Beschreibung
Spezies
Human VEGFR1 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Spezies
human
Rat VEGFR1 ELISA, for serum, plasma and cell culture supernatants,
Spezies
rat

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-FLT1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL0344, purified immunoglobulin, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-1 antibody produced in mouse, clone FLT-11, ascites fluid,
Speziesreaktivität
human
Anwendung
ELISA
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-phospho-VEGFR1 (pTyr1333) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunohistochemistry

western blot
Anti-VEGF Receptor-1 Antibody, Chemicon®, from mouse,
Speziesreaktivität
human, mouse
Anwendung
ELISA
western blot
Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-1 antibody produced in mouse, clone FLT-19, tissue culture supernatant,
Speziesreaktivität
human
Anwendung
ELISA
immunohistochemistry

immunoprecipitation (IP)

microarray

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
SU 4312, ≥98% (HPLC),
Spezies
human
Axitinib, ≥98% (HPLC),
Spezies
human
SU 5416, ≥98% (HPLC),
Spezies
human, mouse
Sunitinib malate, ≥98% (HPLC),
Spezies
human
Pazopanib, ,
Spezies
human

Proteins

Produktnummer
Beschreibung
Spezies
VEGF Receptor-1 (Flt-1)/Fc Chimera human, >90% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder,
Spezies
human
Flt1 active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE),
Spezies
human
FLT1 (784-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human FLT1,
Spezies
human