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ADRA2C

adrenoceptor alpha 2C

Synonyme:
ADRA2L2, ADRA2RL2, ADRARL2, ALPHA2CAR
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(152) Summary: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
  • Mouse(11553) adrenergic receptor, alpha 2c
  • Rat(24175) adrenoceptor alpha 2C
  • domestic guinea pig(100135477) adrenergic receptor, alpha 2c
  • domestic guinea pig(101787589) adrenoceptor alpha 2C
  • cow(101902575) adrenoceptor alpha 2C
  • cow(407139) alpha-2C adrenergic receptor
  • sheep(100170319) adrenoceptor alpha 2C
  • Zebrafish(266752) adrenergic, alpha-2C-, receptor
  • chicken(428799) adrenergic, alpha-2C-, receptor
  • dog(488793) adrenoceptor alpha 2C
  • domestic cat(101087990) adrenoceptor alpha 2C
  • domestic cat(100529244) adrenoceptor alpha 2C

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Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
Clonidin -hydrochlorid, solid,
Spezies
human
Xylazin -hydrochlorid, ≥99.0% (HPLC),
Spezies
human
Guanfacin -hydrochlorid, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Guanfacin -hydrochlorid, ≥98% (HPLC),
Spezies
human
Guanabenz -acetat (Salz), powder,
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
Yohimbin -hydrochlorid, ≥98% (HPLC), powder,
Spezies
human
Idazoxan hydrochloride, ,
Spezies
human
RX 821002 hydrochloride, solid, ≥98% (HPLC),
Spezies
human
UK 14,304, ,
Spezies
human
Mirtazapine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-Alpha 2C Adrenergic Receptor - Apc antibody produced in mouse, clone S330A-80, purified immunoglobulin,
Speziesreaktivität
human, mouse
Anwendung
immunocytochemistry
western blot
Anti-Adrenergic Receptor α-2C antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
western blot
Monoclonal Anti-Alpha 2C Adrenergic Receptor - Atto 390 antibody produced in mouse, clone S330A-80, purified immunoglobulin,
Speziesreaktivität
human, mouse
Anwendung
immunocytochemistry
western blot
Monoclonal Anti-Alpha 2C Adrenergic Receptor - Atto 488 antibody produced in mouse, clone S330A-80, purified immunoglobulin,
Speziesreaktivität
human, mouse
Anwendung
immunocytochemistry
western blot
Monoclonal Anti-Alpha 2C Adrenergic Receptor - Rpe antibody produced in mouse, clone S330A-80, purified immunoglobulin,
Speziesreaktivität
human, mouse
Anwendung
immunocytochemistry
western blot

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
Mianserin -hydrochlorid, ,
Spezies
human
Agmatin -sulfat (Salz), ≥97%, powder,
Spezies
human

Small Molecule - Mixed Agonist/Antagonist

Produktnummer
Beschreibung
Spezies
UK 14,304, ,
Spezies
human
(−)-Norepinephrin, ≥98%, crystalline,
Spezies
human, rat
Haloperidol, powder,
Spezies
human, rat
Clozapin, ,
Spezies
human, rat

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Adra2c,
Spezies
mouse