ACTN4
actinin, alpha 4
Synonyme:
ACTININ-4, FSGS, FSGS1
Spezies:
Human ACTN4 (81), Mouse Actn4 (60595), Rat Actn4 (63836), Zebrafish actn4 (322221), naked mole-rat Actn4 (101710271), domestic cat ACTN4 (101093978), dog ACTN4 (484526), chicken ACTN4 (396024), cow ACTN4 (522269), domestic guinea pig Actn4 (100733111)
UniProtKB-ID:
Gen-ID:
- Human(81) Summary: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq, Jul 2008]
- Mouse(60595) actinin alpha 4
- Rat(63836) actinin alpha 4
- Zebrafish(322221) actinin, alpha 4
- naked mole-rat(101710271) actinin, alpha 4
- domestic cat(101093978) actinin, alpha 4
- dog(484526) actinin, alpha 4
- chicken(396024) actinin, alpha 4
- cow(522269) actinin, alpha 4
- domestic guinea pig(100733111) actinin, alpha 4
- sheep(101111737) actinin, alpha 4
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-ACTN4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-ACTN4 antibody produced in mouse, clone 4D10, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-Alpha Actinin-4 antibody, Rabbit Monoclonal, recombinant, expressed in HEK 293 cells, clone RM287, purified immunoglobulin,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
western blot
Anti-α-Actinin 4 Antibody, clone 1D9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human
Anwendung
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-α-Actinin-4 Antibody, clone 5Y3R6, Rabbit Monoclonal, ,
Speziesreaktivität
human, rat
Anwendung
immunofluorescence
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Proteins
Produktnummer
Beschreibung
Spezies
α-Actinin aus Hühner-Muskelmagen, ~80% α-actinin basis (SDS-PAGE), ammonium sulfate suspension,
Spezies
mouse, chicken, rat, human