1703805

Tylosin

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): Tylosin A
• Empirical Formula (Hill Notation): C₄₆H₇₇NO₁₇
• CAS Number: 1401-69-0
• Molecular Weight: 916.10
• MDL number: MFCD09753818
• UNSPSC Code: 41116107
• NACRES: NA.24
• eCl@ss: 25140904

Properties

• grade: pharmaceutical primary standard
• agency: USP
• API family: tylosin
• manufacturer/tradename: USP
• application(s): USP Biologics; pharmaceutical; pharmaceutical (small molecule); pharmaceutical
• format: neat
• storage temp.: 2-8°C
• InChI: 1S/C46H77NO17/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3/b15-14+,23-18+/t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-/m1/s1
• InChI key: WBPYTXDJUQJLPQ-VMXQISHHSA-N

Description

General description

Find answers to frequently asked questions on USP products in USP FAQs.

Tylosin is a macrolide antibiotic derived from Streptomyces fradiae, primarily used in veterinary medicine. It inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit and is effective against Gram-positive organisms and mycoplasmas. The USP reference standard enables quality control of tylosin-containing drug substances and finished dosage forms.

The USP biologics antibiotics category includes a wide range of antimicrobial agents that are essential in treating bacterial infections. These antibiotics are derived from various natural sources or synthesized to combat specific pathogens effectively. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of antibiotic therapeutics throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

Tylosin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Tylosin Tartrate
• Tylosin Granulated
• Tylosin Injection

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

This product is part of the USP Biologics program.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Safety Information

• Pictograms: GHS08
• Signal Word: Danger
• Hazard Codes: H317,H334
• Precautionary Statements: P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313
• Hazard Classifications: Resp. Sens. 1 - Skin Sens. 1
• Storage Class: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable