1629000

Sulfamethazine

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 4,6-Dimethylsulfadiazine, 4-Amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide, Sulfadimethyldiazine, Sulfadimidine
• Empirical Formula (Hill Notation): C₁₂H₁₄N₄O₂S
• CAS Number: 57-68-1
• Molecular Weight: 278.33
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329751174
• MDL number: MFCD00006066
• Beilstein/REAXYS Number: 261304

Properties

• grade: pharmaceutical primary standard
• agency: USP
• API family: sulfamethazine
• manufacturer/tradename: USP
• application(s): pharmaceutical; pharmaceutical (small molecule)
• format: neat
• SMILES string: Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
• InChI: 1S/C12H14N4O2S/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16)
• InChI key: ASWVTGNCAZCNNR-UHFFFAOYSA-N

Description

General description

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This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Sulfamethazine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monograph such as Sulfamethazine Granulated.

Biochem/physiol Actions

An antimicrobial sulfur drug. Induces CYP3A4 expression and acetylated by N-acetyltransferase. Exhibits sex dependent pharmacokinetics, metabolized by the male specific isoform CYP2C11.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Storage Class: 11 - Combustible Solids
• WGK: WGK 2
• Pictograms: GHS07
• Signal Word: Warning
• Hazard Codes: H315
• Precautionary Statements: P264 - P280 - P302 + P352 - P332 + P313 - P362 + P364
• Hazard Classifications: Skin Irrit. 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable