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1623604

USP

Succinylmonocholine chloride

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

2-(3-Carboxy-1-oxopropoxy)-N,N,N-trimethylethanaminium chloride

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About This Item

Empirical Formula (Hill Notation):
C9H18ClNO4
CAS Number:
5297-17-6
Molecular Weight:
239.70
MDL number:
MFCD00080728
UNSPSC Code:
41116107
NACRES:
NA.24
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grade

pharmaceutical primary standard

API family

succinylcholine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cl.[N+](CCOC(=O)CCC(=O)[O-])(C)(C)C

InChI

1S/C9H17NO4.ClH/c1-10(2,3)6-7-14-9(13)5-4-8(11)12;/h4-7H2,1-3H3;1H

InChI key

LDHMZIUMVSRSIK-UHFFFAOYSA-N

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162350216679051133547
USP

USP

1623604

Succinylmonocholine chloride

Succinylcholine chloride United States Pharmacopeia (USP) Reference Standard

USP

1623502

Succinylcholine chloride

Tizanidine hydrochloride United States Pharmacopeia (USP) Reference Standard

USP

1667905

Tizanidine hydrochloride

Choline chloride United States Pharmacopeia (USP) Reference Standard

USP

1133547

Choline chloride

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

manufacturer/tradename

USP

manufacturer/tradename

USP

manufacturer/tradename

USP

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

format

neat

format

neat

format

neat

format

neat

API family

succinylcholine

API family

succinylcholine

API family

tizanidine

API family

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

-

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Succinylmonocholine chloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monograph such as Succinylcholine Chloride

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Succinylmonocholine identified in negative control tissues.
Marc LeBeau et al.
Journal of analytical toxicology, 27(8), 600-601 (2003-12-17)
M M Andrews et al.
The Journal of pharmacy and pharmacology, 39(3), 173-179 (1987-03-01)
The effects of equimolar concentrations (3.0 X 10(-5) M) of succinylcholine (SCh) and succinylmonocholine (SMC) were studied in-vitro at 20 degrees C in rat extensor digitorum longus muscle (EDL) 0-147 days after common peroneal nerve section. Analysis of simultaneous measurements
Uta Kuepper et al.
International journal of legal medicine, 126(2), 259-269 (2011-09-29)
The muscle relaxant succinylcholine (SUX) evokes respiratory paralysis, and numerous cases of fatal SUX intoxication have been reported. Detection of SUX and its metabolite succinylmonocholine (SMC) is difficult, both due to their (bis-) quaternary structure and the extreme hydrolytic susceptibility
Uta Kuepper et al.
Rapid communications in mass spectrometry : RCM, 22(12), 1965-1970 (2008-05-21)
The determination and quantitation of drugs in biological matrices using high-performance liquid chromatography/tandem mass spectrometry (HPLC/MS/MS) is becoming increasingly popular in analytical toxicology, while at the same time a growing awareness for the limits of this technique can be observed.
Uta Kuepper et al.
Forensic science international, 207(1-3), 84-90 (2010-10-12)
Doubts concerning the applicability of succinylmonocholine (SMC) as a succinylcholine (SUX) marker have been issued. A comparative analysis of previously discussed tissues, i.e. brain, liver and kidney, was conducted to further elucidate this question by searching for diagnostically useful differences
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Global Trade Item Number

SKUGTIN
1623604-50MG04065270799777
1623604-125MG04061833861479

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