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Merck

1508901

USP

Pentoxifylline

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

3,7-Dimethyl-1-(5-oxohexyl)xanthine, Trental

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200 MG

CZK 10,900.00

CZK 10,900.00

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About This Item

Empirical Formula (Hill Notation):
C13H18N4O3
CAS Number:
6493-05-6
Molecular Weight:
278.31
NACRES:
NA.24
PubChem Substance ID:
329750705
UNSPSC Code:
41116107
MDL number:
MFCD00063379

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grade

pharmaceutical primary standard

API family

pentoxifylline

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CN1C=NC2C1C(=O)N(CCCCC(C)=O)C(=O)N2C

InChI

1S/C13H20N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8,10-11H,4-7H2,1-3H3

InChI key

MQGNNJQTNFHNHK-UHFFFAOYSA-N

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1 of 4

This Item
P0510000PHR3218P1784
Pentoxifylline United States Pharmacopeia (USP) Reference Standard

USP

1508901

Pentoxifylline

Pentoxifylline European Pharmacopoeia (EP) Reference Standard

P0510000

Pentoxifylline

Pentoxifylline pharmaceutical secondary standard, certified reference material

Supelco

PHR3218

Pentoxifylline

Pentoxifylline solid

Sigma-Aldrich

P1784

Pentoxifylline

manufacturer/tradename

USP

manufacturer/tradename

EDQM

manufacturer/tradename

-

manufacturer/tradename

-

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

grade

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical

application(s)

-

format

neat

format

neat

format

-

format

-

API family

pentoxifylline

API family

pentoxifylline

API family

pentoxifylline

API family

-

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Pentoxifylline USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Pentoxifylline Compounded Oral Suspension
  • Pentoxifylline Extended-Release Tablets

Biochem/physiol Actions

Phosphodiesterase inhibitor; inhibits synthesis of tumor necrosis factor α (TNF-α).

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H362

Hazard Classifications

Acute Tox. 4 Oral - Lact.

Storage Class

11 - Combustible Solids

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Donghao Lv et al.
The Cochrane database of systematic reviews, (3)(3), CD007677-CD007677 (2009-07-10)
Endometriosis is a chronic, recurring condition that occurs during the reproductive years. It is characterized by endometrial tissue developing outside the uterine cavity. This endometrial tissue development is dependent on estrogen produced primarily by the ovaries and, therefore, traditional management
Donghao Lu et al.
The Cochrane database of systematic reviews, 1, CD007677-CD007677 (2012-01-20)
Endometriosis is a chronic, recurring condition that occurs during the reproductive years. It is characterized by endometrial tissue developing outside the uterine cavity. This endometrial tissue development is dependent on oestrogen produced primarily by the ovaries and, therefore, traditional management
Steven M Shaw et al.
European journal of heart failure, 11(2), 113-118 (2009-01-27)
The progressive syndrome of chronic heart failure (CHF) represents a common disease pathway that may be derived from a host of varying insults (including myocardial ischaemia and infarction, hypertension, viral infection, pregnancy, etc). Despite this multifarious aetiology, a common phenomena
Kate Whitfield et al.
The Cochrane database of systematic reviews, (4)(4), CD007339-CD007339 (2009-10-13)
Alcoholic hepatitis is a life-threatening disease, with an average mortality of approximately 40%. There is no widely accepted, effective treatment for alcoholic hepatitis. Pentoxifylline is used to treat alcoholic hepatitis, but there has been no systematic review to assess its
Seray Külcü Çakmak et al.
Inflammation & allergy drug targets, 11(6), 422-432 (2012-06-12)
Pentoxifylline is methylxanthine derivative which is used in microcirculatory disorders as a vasoactive drug. Novel immunomodulatory properties of pentoxifylline have been reported including the down regulation of tumour necrosis factor-α synthesis and other inflammatory cytokines. Studies have shown that pentoxifylline
View All Related Papers

Global Trade Item Number

SKUGTIN
1508901-200MG04061833860823

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