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Merck

1337809

USP

Imipenem monohydrate

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

(5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid monohydrate, Primaxin monohydrate, Tienam monohydrate

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100 MG

CZK 10,900.00

CZK 10,900.00

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About This Item

Empirical Formula (Hill Notation):
C12H17N3O4S · H2O
CAS Number:
74431-23-5
Molecular Weight:
317.36
NACRES:
NA.24
PubChem Substance ID:
329750155
UNSPSC Code:
41116107
MDL number:
MFCD09753321

Key Documents

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grade

pharmaceutical primary standard

API family

imipenem

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

SMILES string

O.C[C@@H](O)[C@@H]1[C@H]2CC(SCCNC=N)=C(N2C1=O)C(O)=O

InChI

1S/C12H17N3O4S.H2O/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17;/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19);1H2/t6-,7-,9-;/m1./s1

InChI key

GSOSVVULSKVSLQ-JJVRHELESA-N

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1 of 4

This Item
I0160PHR17961392454
Imipenem monohydrate United States Pharmacopeia (USP) Reference Standard

USP

1337809

Imipenem monohydrate

Imipenem monohydrate ≥98% (HPLC)

I0160

Imipenem monohydrate

Imipenem Pharmaceutical Secondary Standard; Certified Reference Material

PHR1796

Imipenem

Meropenem United States Pharmacopeia (USP) Reference Standard

USP

1392454

Meropenem

manufacturer/tradename

USP

manufacturer/tradename

-

manufacturer/tradename

-

manufacturer/tradename

USP

grade

pharmaceutical primary standard

grade

-

grade

certified reference material, pharmaceutical secondary standard

grade

pharmaceutical primary standard

format

neat

format

-

format

-

format

neat

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

API family

imipenem

API family

-

API family

imipenem

API family

meropenem

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-10 to -25°C

storage temp.

-

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Imipenem monohydrate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Imipenem
  • Imipenem and Cilastatin for Injectable Suspension
  • Imipenem and Cilastatin for Injection

Biochem/physiol Actions

Imipenem monohydrate is a broad spectrum B-lactam antibiotic.
Imipenem monohydrate is a broad spectrum B-lactam antibiotic. It is a member of the carbapenem class of "magic bullet" antibiotics for severe infections.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Anne-Laure Michon et al.
Journal of pediatric hematology/oncology, 36(3), e165-e168 (2013-05-15)
Roseomonas are described as opportunistic pathogens rarely involved in human infections. Their identification requires molecular methods and their antimicrobial susceptibility pattern varies according to the species. We report the first case of bacteremia due to Roseomonas mucosa in a child
The deadly impact of extreme drug resistance in Acinetobacter baumannii.
Brad Spellberg et al.
Critical care medicine, 42(5), 1289-1291 (2014-04-17)
Hao-Yuan Lee et al.
Critical care medicine, 42(5), 1081-1088 (2014-01-08)
Acinetobacter baumannii complex bacteremia has been identified increasingly in critical patients admitted in ICUs. Notably, A. baumannii complex bacteremia has a high mortality rate, yet the risk factors associated with mortality remain unclear and controversial. Retrospective study. All adult ICUs
Imipenem heteroresistance: high prevalence among Enterobacteriaceae Klebsiella pneumoniae carbapenemase producers.
Carolina Silva Nodari et al.
Journal of medical microbiology, 64(Pt 1), 124-126 (2014-10-30)
Yi-Jiun Pan et al.
Antimicrobial agents and chemotherapy, 59(2), 1038-1047 (2014-12-03)
Klebsiella pneumoniae is an important human pathogen associated with a variety of diseases, and the prevalence of multidrug-resistant K. pneumoniae (MDRKP) is rapidly increasing. Here we determined the capsular types of 85 carbapenem-resistant K. pneumoniae (CRKP) strains by wzc sequencing

Global Trade Item Number

SKUGTIN
1337809-100MG04061835345502

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