1018505

Amantadine hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 1-Adamantanamine hydrochloride, 1-Adamantylamine hydrochloride, 1-Aminoadamantane hydrochloride, NSC 83653, Tricyclo[3.3.1.1^3,7]decan-1-amine hydrochloride
• Empirical Formula (Hill Notation): C₁₀H₁₇N · HCl
• CAS Number: 665-66-7
• Molecular Weight: 187.71
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329748968
• MDL number: MFCD00074723
• Beilstein/REAXYS Number: 4198854

Properties

• grade: pharmaceutical primary standard
• agency: USP
• API family: amantadine
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule); pharmaceutical
• format: neat
• SMILES string: Cl[H].[H][C@@]12C[C@@]3([H])C[C@@]([H])(C1)CC(N)(C2)C3
• InChI: 1S/C10H17N.ClH/c11-10-4-7-1-8(5-10)3-9(2-7)6-10;/h7-9H,1-6,11H2;1H/t7-,8+,9-,10-;
• InChI key: WOLHOYHSEKDWQH-SOVZANNPSA-N

Description

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Amantadine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Amantadine Hydrochloride Tablets
• Amantadine Hydrochloride Capsules
• Amantadine Hydrochloride Oral Solution
• Memantine Hydrochloride Tablets

Biochem/physiol Actions

Dopamine releaser used to treat Parkinsonism and drug-induced extrapyramidal reactions.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Storage Class: 8A - Combustible corrosive hazardous materials
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• Pictograms: GHS08,GHS05,GHS07
• Signal Word: Danger
• Hazard Codes: H302,H314,H361fd,H412
• Precautionary Statements: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Repr. 2 - Skin Corr. 1B