1013727

Aloin

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 1,8-Dihydroxy-10-(β-D-glucopyranosyl)-3-(hydroxymethyl)-9(10H)-anthracenone, 10-β-D-Glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone, Aloin A, Barbaloin
• Empirical Formula (Hill Notation): C₂₁H₂₂O₉
• CAS Number: 1415-73-2
• Molecular Weight: 418.39
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329748962
• MDL number: MFCD00151160
• Beilstein/REAXYS Number: 6077558

Properties

• grade: pharmaceutical primary standard
• agency: USP
• API family: aloin
• manufacturer/tradename: USP
• application(s): pharmaceutical; pharmaceutical; pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)[C@H]2c3cccc(O)c3C(=O)c4c(O)cc(CO)cc24
• InChI: 1S/C21H22O9/c22-6-8-4-10-14(21-20(29)19(28)17(26)13(7-23)30-21)9-2-1-3-11(24)15(9)18(27)16(10)12(25)5-8/h1-5,13-14,17,19-26,28-29H,6-7H2/t13-,14+,17-,19+,20-,21+/m1/s1
• InChI key: AFHJQYHRLPMKHU-OSYMLPPYSA-N

Description

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Aloin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Aloe
• Aloe Vera Leaf Dry Juice
• Aloe Vera Leaf Juice
• Aloe Vera Leaf Juice Concentrate

Biochem/physiol Actions

Purgative activity in rats requires activation by Eubacterium sp. strain BAR or similar intestinal anaerobe, presumably by conversion to aloe-emodin anthrone.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Codes: H302
• Precautionary Statements: P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable