Skip to Content
Merck

Key Documents

View All Documentation

Skip To

W4387

Wee1, active from rat

N-terminal GST-tagged, solution

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
60 units
Please contact Customer Service for Availability
CZK 21,500.00

About This Item

UNSPSC Code:
12352202
NACRES:
NA.77
MDL number:
MFCD03459055
Biological source:
rat
Recombinant:
expressed in E. coli

CZK 21,500.00

Please contact Customer Service for Availability
​
Request a Bulk Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

rat

Quality Segment

200

recombinant

expressed in E. coli

form

solution

mol wt

~110 kDa

UniProt accession no.

Q63802

application(s)

cell analysis

shipped in

dry ice

storage temp.

−70°C

Gene Information

rat ... Wee1(308937)

Application

Wee1, active from rat may be used to study apoptotic signaling.

Biochem/physiol Actions

Protein inhibitor of Cdk2 kinase
Wee1 is a protein tyrosine kinase that phosphorylates Cdc2 on Tyr15 and hence inactivates the CDK1 and CDK2, which facilitates in the negative regulation of entry of cells into mitosis.[1] Increased level of wee1 stimulates Human Immunodeficiency Virus type 1 (HIV-1) Vpr induced cell cycle arrest at G2/M transition followed by apoptosis.[2]

Physical form

Solution in 50 mM Tris-HCl, pH 7.5, 1 mM EDTA, 1 mM DTT, 10% Glycerol

Other Notes

One unit of Wee 1 is defined as the amount of Wee 1 which inhibits 90% of the activity of 10 units of Cdk2

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
SRP5247SRP5219SRP5242
Wee1, active from rat N-terminal GST-tagged, solution

Sigma-Aldrich

W4387

Wee1, active from rat

PDHK1, active, GST tagged human PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Sigma-Aldrich

SRP5247

PDHK1, active, GST tagged human

KAT3A (518-1207), GST tagged human recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Sigma-Aldrich

SRP5219

KAT3A (518-1207), GST tagged human

ERK5, active, GST tagged human PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Sigma-Aldrich

SRP5242

ERK5, active, GST tagged human

Gene Information

rat ... Wee1(308937)

Gene Information

human ... PDK1(5163)

Gene Information

human ... CREBBP(1387)

Gene Information

human ... MAPK7(5598)

biological source

rat

biological source

human

biological source

human

biological source

human

form

solution

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

application(s)

cell analysis

application(s)

cell analysis

application(s)

cell analysis

application(s)

cell analysis

recombinant

expressed in E. coli

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected Sf9 cells

storage temp.

−70°C

storage temp.

−70°C

storage temp.

−70°C

storage temp.

−70°C

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Questions

Reviews

No rating value

Active Filters