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V2501

Snake venom

from Vipera russelli (Russell’s Viper), anti-bacterial toxin

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About This Item

UNSPSC Code:
12352202
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Product Name

Snake venom from Vipera russelli (Russell′s Viper),

Quality Segment

200

storage temp.

−20°C

Application

Snake venom from Vipera russelli (Russell′s Viper) has been used for extraction of coagulant protein for complex generation with bovine X factor.
Snake venom from Vipera russelli (Russell′s Viper) has also been used as a positive control in indirect and sandwich enzyme-linked immunosorbent assay (ELISA) to study the performance of the immunochromatographic test (ICT)-Viper in venom detection in vitro and the detection of clinical envenoming, respectively.[1]

Biochem/physiol Actions

Snake venom from Russell′s Viper is rich in toxins and proteinase inhibitors. The receptor from Vipera russelli β-RTX, interacts with monoamines and opiate and prevents their interaction with native receptors. The proteases from Russell′s Viper mediate coagulation in human plasma. The neurotoxicity of the venom is contributed by phospholipases.
Snake venom can impose death on humans and animals.[2] Nevertheless, snake venom also exhibits anti-bacterial and wound healing properties. Therefore, it is used as a therapeutic for treating various diseases including thrombosis, arthritis, and cancer.[2]

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

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Questions

1–2 of 2 Questions  

  1. How can V2501 be diluted? Where can I find the documentation for this process?

    1 answer

    1. The supplier has provided the following information: store the powder at -20°C and dissolve it in sterile water, typically at 20 mg/ml. The solution may appear slightly hazy. It is recommended to store the solution in aliquots at -80°C, but -20°C is suitable for a short period of time, although the supplier does not define what is meant by a 'short period'. It is advised to avoid repeated freezing and thawing cycles, and the supplier suggests aliquoting the product once in solution.

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  2. Origin of venom RVV, do you issue Cites certificate?

    1 answer

    1. See the link below to review a sample Certificate of Origin for this product:
      https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COO/Q12/V2501-100MGSLCL9857.pdf

      These documents are lot-specific and may be supplied by our Technical Service team. We kindly ask you to navigate to the link https://www.sigmaaldrich.com/techservice, click on "Product Documentation" under the Products Section with all the required information so that a member of our team can reach out to you to assist further. Thank you.

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