PEG-Link is comprised of polyethylene glycol and thiol (SH) groups at each end. The thiol groups form stable thioether bond with thiol-reactive groups of the polymers (Mal-PVA, Mal-Dextran, SG-PVA and SG-Dextran), which results in stable hydrogel. The matrix metalloproteases secreted by cells cannot cleave PEG crosslinker.
Application
TRUEPEG is used to crosslink PVA and dextran polymers to generate stable hydrogel.
Features and Benefits
Non-MMP degradable.
Components
TRUEPEG contains PEG non cell-degradable crosslinker lyophilized and water.
Caution
Avoid prolong exposure of PEG non cell-degradable crosslinker to air.
TrueGel3D™ is a synthetic hydrogels platform for 3D cell culture that aim to mimic the natural extracellular environment for more physiological culture conditions
An advanced protocol is available for TrueGel 3D kits for 3D cell culture for peptides concentration or stiffness optimisation
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