T8761

Tyloxapol

nonionic surfactant

• Synonym(s): 4-(1,1,3,3-Tetramethylbutyl)phenol polymer with formaldehyde and oxirane
• CAS Number: 25301-02-4
• NACRES: NA.25
• PubChem Substance ID: 24900557
• UNSPSC Code: 12161900
• MDL number: MFCD00149002

Properties

• Quality Segment: 200
• CMC: 0.018 mM
• transition temp: cloud point 94.3 °C
• solubility: water: miscible
• SMILES string: [H]C([H])=O.OCCO.CC(C)(C)CC(C)(C)c1ccc(O)cc1
• InChI: 1S/C14H22O.C2H6O2.CH2O/c1-13(2,3)10-14(4,5)11-6-8-12(15)9-7-11;3-1-2-4;1-2/h6-9,15H,10H2,1-5H3;3-4H,1-2H2;1H2
• InChI key: GWJOFBXSBDVUMH-UHFFFAOYSA-N

Description

General description

A nonionic liquid polymer of the alkyl aryl polyether alcohol type. Used as a surfactant.

Application

Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type. It is used as a surfactant to aid liquefaction. Tyloxapol is used in the development of non-ionic surfactant-based liposomes (niosomes) for use in drug delivery systems. Tyloxapol may be used to study its mechanism of protecting macrophages from endotoxins. Tyloxapol may be used to study is potential cell toxicitiy.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk: WGK 2
• flash_point_f: 235.4 °F - closed cup
• flash_point_c: 113 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter