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T3411

Tetramethylammonium chloride solution

Molecular Biology

Synonym(s):

N,N,N-Trimethylmethanaminium chloride

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Size/SKUAvailabilityPrice
500 mL
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CZK 5,530.00
1 L
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CZK 9,190.00

About This Item

CAS Number:
NACRES:
NA.31
PubChem Substance ID:
UNSPSC Code:
12352107
MDL number:

CZK 5,530.00


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grade

Molecular Biology

Quality Segment

concentration

5 M

foreign activity

DNase, RNase, none detected

SMILES string

[Cl-].C[N+](C)(C)C

InChI

1S/C4H12N.ClH/c1-5(2,3)4;/h1-4H3;1H/q+1;/p-1

InChI key

OKIZCWYLBDKLSU-UHFFFAOYSA-M

General description

Tetramethylammonium binds AT-rich DNA polymers while concomitantly abolishing the preferential melting of AT versus GC base pairs. It is supplied as a 0.2 μm filtered solution in 18 megohm water.

Application

Tetramethylammonium chloride solution (TMAC) has been used:
  • in the preparation of hybridization cocktail for array hybridization and scanning
  • in next-generation sequencing (NGS), and genome-wide unbiased identification of double-stranded breaks enabled by sequencing (GUIDE-seq) library preparation
  • in the preparation of TMAC buffer and bead hybridization mixture for hybridization and detection


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8661486870334901
grade

Molecular Biology

grade

Molecular Biology

grade

-

grade

-

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

200

foreign activity

DNase, RNase, none detected

foreign activity

-

foreign activity

-

foreign activity

-

concentration

5 M

concentration

-

concentration

-

concentration

25 wt. % in methanol




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Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. At what temperature is this product stored?

    1 answer
    1. This product may be stored in room temperature.

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