Skip to Content
Merck

Key Documents

View All Documentation

Skip To

T3202

Torsemide

≥98% (HPLC), solid

Synonym(s):

Demadex, N-[[(1-Methylethyl)amino]carbonyl]-4-[(3-methylphenyl)amino]-3-pyridinesulfonamide

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
10 mg
Please contact Customer Service for Availability
CZK 3,910.00
50 mg
Please contact Customer Service for Availability
CZK 12,200.00
CZK 10,370.00

About This Item

Empirical Formula (Hill Notation):
C16H20N4O3S
CAS Number:
56211-40-6
Molecular Weight:
348.42
NACRES:
NA.77
PubChem Substance ID:
329826741
UNSPSC Code:
12352200
MDL number:
MFCD00866166
Assay:
≥98% (HPLC)
Form:
solid

CZK 3,910.00

Please contact Customer Service for Availability
​
Request a Bulk Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Segment

100

assay

≥98% (HPLC)

form

solid

solubility

DMSO: soluble 18 mg/mL, H2O: insoluble

originator

Roche

SMILES string

CC(C)NC(=O)NS(=O)(=O)c1cnccc1Nc2cccc(C)c2

InChI

1S/C16H20N4O3S/c1-11(2)18-16(21)20-24(22,23)15-10-17-8-7-14(15)19-13-6-4-5-12(3)9-13/h4-11H,1-3H3,(H,17,19)(H2,18,20,21)

InChI key

NGBFQHCMQULJNZ-UHFFFAOYSA-N

Gene Information

human ... SLC12A1(6557)

Application

Torsemide has been used as an inhibitor of Na+ Cl- co-transporter in transgenic Arabidopsis thaliana plants1.

Biochem/physiol Actions

Torsemide functions in the thick ascending limb of the loop of Henle and enhances the excretion of sodium, chloride and water from the luminal side of the cells. Furthermore, torsemide can treat oedematous conditions that are associated with diseases such as liver cirrhosis, kidney disorders and chronic congestive heart failure2.
Torsemide is a loop diuretic and inhibitor of the Na+/K+/2Cl- carrier system.
Torsemide is a loop diuretic of the pyridine-sulfonylurea class with antialdosteronergic properties and inhibitor of the Na+/K+/2Cl- carrier system.

Features and Benefits

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Preparation Note

Torsemide is soluble in DMSO at 18 mg/ml and is insoluble in water.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
1672304Y0000461Y0000462
Torsemide ≥98% (HPLC), solid

Sigma-Aldrich

T3202

Torsemide

Torsemide United States Pharmacopeia (USP) Reference Standard

USP

1672304

Torsemide

Torasemide anhydrous European Pharmacopoeia (EP) Reference Standard

Y0000461

Torasemide anhydrous

Torasemide for system suitability European Pharmacopoeia (EP) Reference Standard

Y0000462

Torasemide for system suitability

form

solid

form

-

form

-

form

-

assay

≥98% (HPLC)

assay

-

assay

-

assay

-

Quality Level

100

Quality Level

-

Quality Level

-

Quality Level

-

solubility

DMSO: soluble 18 mg/mL, H2O: insoluble

solubility

-

solubility

-

solubility

-

Gene Information

human ... SLC12A1(6557)

Gene Information

human ... SLC12A1(6557)

Gene Information

human ... SLC12A1(6557)

Gene Information

human ... SLC12A1(6557)

originator

Roche

originator

-

originator

-

originator

-

Still not finding the right product?

Explore all of our products under Torsemide

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Questions

Reviews

No rating value

Active Filters