Unfortunately, this product is not tested to determine the identity of any impurities.
T3125
Tetrahydrofolic acid
≥65% (when packaged), powder
Synonym(s):
5,6,7,8-Tetrahydropteroyl-L-glutamic acid, THF
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| Size/SKU | Availability | Price |
|---|---|---|
25 mg | Please contact Customer Service for Availability | CZK 1,760.00 |
100 mg | Please contact Customer Service for Availability | CZK 4,800.00 |
1 g | Please contact Customer Service for Availability | CZK 24,400.00 |
About This Item
Empirical Formula (Hill Notation):
C19H23N7O6
CAS Number:
Molecular Weight:
445.43
UNSPSC Code:
12352204
NACRES:
NA.51
PubChem Substance ID:
EC Number:
205-181-1
Beilstein/REAXYS Number:
9238187
MDL number:
Form:
powder
Solubility:
0.1 M phosphate pH 7.0: soluble-5 mg/mL, clear to slightly hazy, light yellow to brownish-yellow
Biological source:
synthetic
Color:
faintly yellow to light brown
CZK 1,760.00
Please contact Customer Service for Availability
biological source
synthetic
Quality Segment
form
powder
concentration
≥65% (when packaged)
color
faintly yellow to light brown
solubility
0.1 M phosphate pH 7.0: soluble-5 mg/mL, clear to slightly hazy, light yellow to brownish-yellow
storage temp.
−20°C
SMILES string
NC1=NC2=C(NC(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)CN2)C(=O)N1
InChI
1S/C19H23N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,11-12,21,23H,5-8H2,(H,24,29)(H,27,28)(H,31,32)(H4,20,22,25,26,30)/t11?,12-/m0/s1
InChI key
MSTNYGQPCMXVAQ-KIYNQFGBSA-N
Application
Tetrahydrofolic acid has been used to determine the inhibitory effect of tetrahydrofolate on polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs). A recent use of tetrahydrofolate (THF) is for studying the activation of riboswitches.
Tetrahydrofolic acid may also be used as a standard to generate calibration curve to quantify the folate types produced by Streptococcus thermophilus in milk cultures using high-performance liquid chromatography (HPLC).[1] It is also suitable for use in the enzymatic assay of formate-tetrahydrofolate ligase from M. extorquens (MeFtfL).[2]
Biochem/physiol Actions
Tetrahydrofolic acid is the parent molecule of the folate derivatives that donate one-carbon units to amino acids, nucleic acids, and lipids. Tetrahydrofolate metabolites participate in the synthesis of purine and pyrimidine and in synthesis and conversion of amino acids
Packaging
Sealed ampule.
1 of 1
This Item | |||
|---|---|---|---|
| solubility 0.1 M phosphate pH 7.0: soluble-5 mg/mL, clear to slightly hazy, light yellow to brownish-yellow | solubility water: 25 mg/mL | solubility - | solubility - |
| biological source synthetic | biological source - | biological source synthetic (organic) | biological source - |
| Quality Level 200 | Quality Level 300 | Quality Level 200 | Quality Level 100, 400 |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| color faintly yellow to light brown | color - | color light yellow to dark yellow-orange | color - |
| form powder | form powder | form powder | form powder |
wgk
WGK 3
flash_point_c
No data available
ppe
Eyeshields, Gloves, type N95 (US)
signalword
Warning
hcodes
Hazard Classifications
Self-heat. 2 - Skin Sens. 1
Storage Class
4.2 - Pyrophoric and self-heating hazardous materials
flash_point_f
No data available
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