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T2320

T0901317

≥98%

Synonym(s):

N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide

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Size/SKUAvailabilityPrice
5 mg
Please contact Customer Service for Availability
CZK 2,340.00
10 mg
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CZK 3,590.00

About This Item

Empirical Formula (Hill Notation):
C17H12NSO3F9
CAS Number:
293754-55-9
Molecular Weight:
481.33
NACRES:
NA.25
PubChem Substance ID:
24900032
UNSPSC Code:
12352106
MDL number:
MFCD03412028
Assay:
≥98%

CZK 2,340.00

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Quality Segment

200

assay

≥98%

mol wt

481.3

storage temp.

−20°C

SMILES string

OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c2ccccc2)(C(F)(F)F)C(F)(F)F

InChI

1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2

InChI key

SGIWFELWJPNFDH-UHFFFAOYSA-N

Gene Information

human ... ABCA1(19), NR1H2(7376), NR1H3(10062)

Application

T0901317 has been used in LXR agonist study in order to observe the expression of all dietary cholesterol-regulated genes in mice. It has also been used to stimulate the radiolabeled peritoneal macrophages from WT (wildtype) and Tg (transgenic) mice for cellular cholesterol efflux assay.

Biochem/physiol Actions

LXR agonist whose treatment results in an LXR-dependent up-regulation of ABC1 gene expression
T0901317 can prevent the secretion of insulin by acting on the metabolism of mitochondria.

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575310752924411140
T0901317 ≥98%

Sigma-Aldrich

T2320

T0901317

T0901317 A cell-permeable, nonsterol, benzenesulfonamide compound that acts as a highly selective and potent liver X receptor agonist (EC50 of 20 nM for LXRα).

Sigma-Aldrich

575310

T0901317

2,2,2-Trifluoroethyl trifluoromethanesulfonate 95%

Sigma-Aldrich

752924

2,2,2-Trifluoroethyl trifluoromethanesulfonate

(S)-(+)-α-(Trifluoromethyl)benzyl alcohol 99%

Sigma-Aldrich

411140

(S)-(+)-α-(Trifluoromethyl)benzyl alcohol

assay

≥98%

assay

≥98% (HPLC)

assay

95%

assay

99%

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

200

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

-

mol wt

481.3

mol wt

-

mol wt

-

mol wt

-

Gene Information

human ... ABCA1(19), NR1H2(7376), NR1H3(10062)

Gene Information

-

Gene Information

-

Gene Information

-

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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