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T0195

α-Bungarotoxin-tetramethylrhodamine

from Bungarus multicinctus (Formosan Banded Krait), Nicotinic acetylcholine receptor antagonist

Synonym(s):

TMR-α-BTX

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Size/SKUAvailabilityPrice
0.5 mg
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9 990,00 CZK

About This Item

UNSPSC Code:
12352116
NACRES:
NA.77
MDL number:

9 990,00 CZK


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Product Name

α-Bungarotoxin-tetramethylrhodamine from Bungarus multicinctus (Formosan Banded Krait),

mol wt

~8,500

Quality Segment

color

red

solubility

H2O: soluble

storage temp.

−20°C

Application

α-Bungarotoxin-tetramethylrhodamine from Bungarus multicinctus (Formosan Banded Krait) has been used in immunofluorescence staining (1:200) for identification of neuromuscular junction in experimental models. It has also been used to block muscle contraction in myotome cells.
α-Bungarotoxin-tetramethylrhodamine from Bungarus multicinctus was used at a dilution of 1:220 to identify the distribution of nicotinic acetylcholine receptors at neuromuscular junctions of longitudinal sections of rat gastrocnemius muscle.

Biochem/physiol Actions

Useful for detecting the distribution of nicotinic acetylcholine receptors at neuromuscular junctions.
α-Bungarotoxin is a high-affinity antagonist for nicotinic acetylcholine receptors (AChRs) from muscle but not the neurons. Labeling α-Bungarotoxin with tetramethylrhodamine enables the detection of bungarotoxin-binding receptors at neuromuscular junctions.

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This Item
203980203732C2020
description

-

description

from Bungarus multicinctus, lyophilized solid, irreversible binder to motor end-plate acetylcholine receptor, Calbiochem®

description

Lipid-soluble polyether neurotoxin that binds to Na+ channels on nerves and muscles causing an excessive influx of Na+ across membranes.

description

≥98% (TLC), powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

mol wt

~8,500

mol wt

-

mol wt

-

mol wt

-

solubility

H2O: soluble

solubility

PBS: soluble, water: soluble

solubility

methanol: soluble, ethyl acetate: soluble, water: soluble

solubility

H2O: slightly soluble, methanol: water: soluble, polar organic solvents: soluble

color

red

color

-

color

tan to white

color

yellow


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



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