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SML3605

Selexipag

≥98% (HPLC)

Synonym(s):

2-{4-[(5,6-Diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}-N-(methylsulfonyl)acetamide, ACT-293987, NS-304

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Size/SKUAvailabilityPrice
10 mg
Please contact Customer Service for Availability
2 030,00 CZK
50 mg
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8 200,00 CZK

About This Item

Empirical Formula (Hill Notation):
C26H32N4O4S
CAS Number:
Molecular Weight:
496.62
UNSPSC Code:
51111800
NACRES:
NA.21
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

2 030,00 CZK


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

SMILES string

CC(C)N(CCCCOCC(NS(C)(=O)=O)=O)C1=NC(C2=CC=CC=C2)=C(C3=CC=CC=C3)N=C1

InChI key

QXWZQTURMXZVHJ-UHFFFAOYSA-N

Biochem/physiol Actions

Potent, highly selective and orally available agonist for the PGI2 receptor (IP receptor); nonprostanoid IP receptor agonist
Selexipag is a potent, highly selective and orally available nonprostanoid agonist for the PGI2 receptor (IP receptor). Selexipag is readily hydrolyzed to the active metabolite ACT-333679 (MRE-269), which is also a potent and selective agonist at IP receptors. In contrast to the prostacyclin analogs iloprost and beraprost, selexipag and metabolite ACT-333679 does not contract gastric fundus up to mM concentrations.

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This Item
SML3678SML0827SML3512
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

-10 to -25°C

storage temp.

-10 to -25°C

storage temp.

−20°C

storage temp.

-10 to -25°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

color

white to beige

color

white to beige

color

white to beige

color

white to beige


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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