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SML3588

J147

≥98% (HPLC)

Synonym(s):

(E)-N-(2,4-dimethylphenyl)-2,2,2-trifluoro-N′-(3-methoxybenzylidene)acetohydrazide, 2,2,2-Trifluoro-acetic acid 1-(2,4-dimethylphenyl)-2-[(3-methoxyphenyl)methylene]hydrazide, J 147

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Size/SKUAvailabilityPrice
5 mg
Please contact Customer Service for Availability
1 980,00 CZK
25 mg
Please contact Customer Service for Availability
8 000,00 CZK

About This Item

Empirical Formula (Hill Notation):
C18H17F3N2O2
CAS Number:
Molecular Weight:
350.33
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

1 980,00 CZK


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (Warmed)

storage temp.

2-8°C

SMILES string

COC1=CC(/C=N/N(C2=C(C=C(C=C2)C)C)C(C(F)(F)F)=O)=CC=C1

InChI

1S/C18H17F3N2O2/c1-12-7-8-16(13(2)9-12)23(17(24)18(19,20)21)22-11-14-5-4-6-15(10-14)25-3/h4-11H,1-3H3/b22-11+

InChI key

HYMZAYGFKNNHDN-SSDVNMTOSA-N

Biochem/physiol Actions

Broadly neuroprotective agent that enhances the memory in normal and Alzheimer’s disease (AD) transgenic mice
J147 is a broadly neuroprotective (in multiple assays) compound that enhances the memory in normal and Alzheimer’s disease (AD) transgenic mice. J147 has neurotrophic and BDNF-like activities that are independent of the BDNF receptor, and TrkB. Also it appears that J147 has a small but significant effect on Ab metabolism by reducing Ab1–42 in the soluble fraction of the hippocampus.

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This Item
AV30009CB_90110605CB_91081920
vibrant-m

DA6.147

vibrant-m

C0147

description

≥98% (HPLC)

description

IgG fraction of antiserum

description

90110605, NOTE: Both the cell line and DNA from the cell line may be available for this product. Please choose -1VL or VIAL for cells, or -DNA-5UG for DNA., Reactivity: Anti-MHC class II α-chain, human

description

NOTE: Both the cell line and DNA from the cell line may be available for this product. Please choose -1VL or VIAL for cells, or -DNA-5UG for DNA.

assay

≥98% (HPLC)

assay

-

assay

-

assay

-

form

powder

form

buffered aqueous solution

form

-

form

-

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

-

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−196°C

storage temp.

-

solubility

DMSO: 2 mg/mL, clear (Warmed)

solubility

-

solubility

-

solubility

-

color

white to beige

color

-

color

-

color

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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