SML3542
SGC-UBD253
≥98% (HPLC)
Synonym(s):
3-(8-Chloro-3-(2-(2-methoxybenzylamino)-2-oxoethyl)-4-oxo-3,4-dihydroquinazolin-2-yl)propanoic acid
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
| Size/SKU | Availability | Price |
|---|
About This Item
Empirical Formula (Hill Notation):
C21H20ClN3O5
Molecular Weight:
429.85
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Pricing and availability is not currently available.
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (Warmed)
storage temp.
2-8°C
SMILES string
O=C(NCC(C=CC=C1)=C1OC)CN(C(CCC(O)=O)=N2)C(C3=C2C(Cl)=CC=C3)=O
Biochem/physiol Actions
Cell penetrant, potent and selective chemical probe for the ubiquitin binding domain (UBD) of HDAC6 (histone deacetylase 6)
SGC-UBD253 is a cell penetrant, potent and selective chemical probe for the ubiquitin binding domain (UBD) of HDAC6 (histone deacetylase 6). SGC-UBD253 potently binds to HDAC6 UBD (KD = 84 nM) and inhibits the HDAC6-ISG15 interaction (EC50 = 1.9 µM).
1 of 1
This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: 2 mg/mL, clear (Warmed) | solubility DMSO: 2 mg/mL, clear | solubility DMSO: 2 mg/mL, clear (warmed) | solubility DMSO: 2 mg/mL, clear |
| color white to beige | color white to beige | color white to beige | color white to beige |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.