SML3391

Glatiramer acetate

≥95% (HPLC), Myelin basic protein mimetic, powder or Lyophilized powder or film

• Synonym(s): Cop 1 (polyamide), Cop-1, Copaxone, Copolymer 1, GA, Polymer with L-alanine, L-lysine, L-tyrosine, and L-glutamic acid acetate
• Linear Formula: (C₉H₁₁NO₃)_a·(C₆H₁₄N₂O₂)_b ·(C₅H₉NO₄)_c ·(C₃H₇NO₂)_d ·x(CH₃CO₂H)
• UNSPSC Code: 12352200
• NACRES: NA.21
• Assay: ≥95% (HPLC)
• Form: (Powder or Lyophilized powder or film)
• Storage condition: desiccated

Properties

• Product Name: Glatiramer acetate, ≥95% (HPLC)
• Quality Segment: 100
• assay: ≥95% (HPLC)
• form: (Powder or Lyophilized powder or film)
• storage condition: desiccated
• color: white to beige
• storage temp.: -10 to -25°C
• SMILES string: OC([C@@H](N)C)=O.OC(CC[C@H](N)C(O)=O)=O.NCCCC[C@H](N)C(O)=O.OC([C@@H](N)CC1=CC=C(C=C1)O)=O
• InChI: 1S/C9H11NO3.C6H14N2O2.C5H9NO4.C3H7NO2/c10-8(9(12)13)5-6-1-3-7(11)4-2-6;7-4-2-1-3-5(8)6(9)10;6-3(5(9)10)1-2-4(7)8;1-2(4)3(5)6/h1-4,8,11H,5,10H2,(H,12,13);5H,1-4,7-8H2,(H,9,10);3H,1-2,6H2,(H,7,8)(H,9,10);2H,4H2,1H3,(H,5,6)/t8-;5-;3-;2-/m0000/s1
• InChI key: YLOCGHYTXIINAI-XKUOMLDTSA-N

Description

Biochem/physiol Actions

Glatiramer acetate, a myelin basic protein mimetic, is an immunomodulator used for treatment of Multiple Sclerosis. Glatiramer acetate is a mixture of synthetic peptides randomly composed of glutamic acid, lysine, alanine, and tyrosine. It reduces relapse rate and disease progression in Multiple Sclerosis. Its mechanism of action is not fully understood. Glatiramer acetate generates anti-inflammatory Th2 cells, which produce neurotrophic factors.

Myelin basic protein mimetic; immunodmodulator; used to treat multiple sclerosis; generates anti-inflammatory Th2 cells, which produce neurotrophic factors; promotes neurogenesis

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable