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SML2911

dBRD9 Hydrochloride

≥97% (HPLC)

Synonym(s):

2-[[[4-(1,2-Dihydro-2-methyl-1-oxo-2,7-naphthyridin-4-yl)-2,6-dimethoxyphenyl]methyl]methylamino]-N-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethyl]acetamide Hydrochloride, Naphthiridinone degrader 6 Hydrochloride

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Size/SKUAvailabilityPrice
1 mg
Please contact Customer Service for Availability
1 030,00 CZK
5 mg
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5 640,00 CZK

About This Item

Empirical Formula (Hill Notation):
C40H45N7O10 · xHCl
Molecular Weight:
783.83 (free base basis)
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥97% (HPLC)
Form:
powder
Storage condition:
desiccated

1 030,00 CZK


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ligand

pomalidomide

Quality Segment

assay

≥97% (HPLC)

form

powder

storage condition

desiccated

technique(s)

targeted protein degradation: suitable

color

white to beige

solubility

H2O: 2 mg/mL, clear

storage temp.

−20°C

Biochem/physiol Actions

cell permeable, potent and selective BRD9-directed chemical degrader
dBRD9 is a cell permeable, potent and selective BRD9-directed chemical degrader that bridges the BRD9 bromodomain and the cereblon E3 ubiquitin ligase complex. dBRD9 exhibits a potent anti-proliferative activity in human AML lines.

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description

≥98% (HPLC)

form

powder

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

form

powder

assay

≥97% (HPLC)

assay

-

assay

-

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

100

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

solubility

H2O: 2 mg/mL, clear

solubility

-

solubility

-

solubility

DMSO: 20 mg/mL, clear

storage condition

desiccated

storage condition

-

storage condition

-

storage condition

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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