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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Please contact Customer Service for Availability | 1 530,00 CZK 1 300,50 CZK |
25 mg | Please contact Customer Service for Availability | 6 230,00 CZK |
About This Item
Empirical Formula (Hill Notation):
C15H11Cl2NO4
CAS Number:
Molecular Weight:
340.16
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
1 300,50 CZK
List Price1 530,00 CZKSave 15%Web-Only Promotion
Please contact Customer Service for Availability
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
Clc1c(cccc1)OCC(=O)Nc2c(ccc(c2)Cl)C(=O)O
InChI
1S/C15H11Cl2NO4/c16-9-5-6-10(15(20)21)12(7-9)18-14(19)8-22-13-4-2-1-3-11(13)17/h1-7H,8H2,(H,18,19)(H,20,21)
InChI key
CVQCJPCMPGKEDH-UHFFFAOYSA-N
Biochem/physiol Actions
CBA (Compound 5; 4-Chloro-2-[[2-(2-chlorophenoxy)acetyl]amino]benzoic acid) is a cell penetrant, potent and selective TRPM4 (Transient receptor potential melastatin member 4) inhibitor that shows not significant activity against TRPM5, TRPM7, TRPM8, TRPV1, TRPV3, TRPV6. It rescues functional expression of mutant A432T TRPM4 in cells. CBA (Compound 5) exhibits neuroprotective activity against glutamate-induced neurodegeneration.
cell penetrant, potent and selective TRPM4 (Transient receptor potential melastatin member 4) inhibitor
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This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥98% (HPLC) | description - | description ≥98% (HPLC) |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: 2 mg/mL, clear | solubility DMSO: 2 mg/mL, clear | solubility DMSO: 25 mg/mL, clear | solubility DMSO: 15 mg/mL, clear |
| color white to beige | color white to beige | color white to beige | color white to brown |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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