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Merck

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SML2593

MS0021570

≥98% (HPLC)

Synonym(s):

5-(Benzylsulfanyl)-N-methyl-1,3,4-thiadiazol-2-amine, 5-(Benzylthio)-N-methyl-1,3,4-thiadiazol-2-amine, MS 21570, MS0021570_1, N-Methyl-5-[(phenylmethyl)thio]-1,3,4-thiazadiazol-2-amine

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Size/SKUAvailabilityPrice
5 mg
Please contact Customer Service for Availability
1 700,00 CZK
1 445,00 CZK
25 mg
Please contact Customer Service for Availability
8 500,00 CZK
7 225,00 CZK

About This Item

Empirical Formula (Hill Notation):
C10H11N3S2
CAS Number:
Molecular Weight:
237.34
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

1 445,00 CZK

List Price1 700,00 CZKSave 15%
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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

[s]1c(nnc1NC)SCc2ccccc2

InChI

1S/C10H11N3S2/c1-11-9-12-13-10(15-9)14-7-8-5-3-2-4-6-8/h2-6H,7H2,1H3,(H,11,12)

InChI key

KFLNRVSOQJTXDG-UHFFFAOYSA-N

Biochem/physiol Actions

GPR171 antagonist
MS0021570 is a potent antagonist of GPR171, a G protein-coupled receptor of BigLEN (b-LEN), which is a neuropeptide derived from proSAAS and involved in regulation of feeding. MS0021570 had a IC50 value of 220 nM. It was shown to block inceases in food intake and to reduce anxiety-like behavior and fear conditioning in mice.

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SML2472SML0720SML0136
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

room temp

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: ≥8 mg/mL

color

white to beige

color

white to pink

color

white to beige

color

white to tan


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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