Skip to Content
Merck

Skip To

SML2524

Fexinidazole

≥98% (HPLC)

Synonym(s):

1-methyl-2-[[4-(methylthio)phenoxy]methyl]-5-nitro-1H-imidazole, HOE 239

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
5 mg
Please contact Customer Service for Availability
3 210,00 CZK
25 mg
Please contact Customer Service for Availability
12 900,00 CZK

About This Item

Empirical Formula (Hill Notation):
C12H13N3O3S
CAS Number:
Molecular Weight:
279.31
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

3 210,00 CZK


Please contact Customer Service for Availability

​
Request a Custom Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


assay

≥98% (HPLC)

form

powder

color

light yellow to dark brown

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

CN1C(COC2=CC=C(SC)C=C2)=NC=C1[N+]([O-])=O

InChI

1S/C12H13N3O3S/c1-14-11(13-7-12(14)15(16)17)8-18-9-3-5-10(19-2)6-4-9/h3-7H,8H2,1-2H3

InChI key

MIWWSGDADVMLTG-UHFFFAOYSA-N

Biochem/physiol Actions

Anti Trypanosoma, Leishmania agent.
Fexinidazole is a potent anti-Trypanosoma agent. Trypanosoma species human protozoan pathogens are responsible for sleeping sickness and Chagas disease. In vivo, fexinidazole is oxidized to sulfoxide and sulfone metabolites that are effective in blocking the progression of the parasitic disease visceral leishmaniasis. The mechanism of action appears to be by reductive activation via an NADH-dependent nitroreductase expressed by the parasites.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
239765C7698SML1019
description

≥98% (HPLC)

description

InSolution, 100 mg/mL in DMSO, Suitable for cell culture

description

from microbial, ≥94% (TLC)

description

≥98% (HPLC)

form

powder

form

solution

form

powder

form

powder

assay

≥98% (HPLC)

assay

-

assay

≥94% (TLC)

assay

≥98% (HPLC)

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: soluble

solubility

ethanol: soluble, clear to hazy

solubility

H2O: 20 mg/mL, clear

color

light yellow to dark brown

color

-

color

white to off-white

color

white to beige


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library




Questions

Reviews

No rating value

Active Filters