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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Please contact Customer Service for Availability | 3 210,00 CZK |
25 mg | Please contact Customer Service for Availability | 12 900,00 CZK |
About This Item
Empirical Formula (Hill Notation):
C12H13N3O3S
CAS Number:
Molecular Weight:
279.31
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
light yellow to dark brown
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
SMILES string
CN1C(COC2=CC=C(SC)C=C2)=NC=C1[N+]([O-])=O
InChI
1S/C12H13N3O3S/c1-14-11(13-7-12(14)15(16)17)8-18-9-3-5-10(19-2)6-4-9/h3-7H,8H2,1-2H3
InChI key
MIWWSGDADVMLTG-UHFFFAOYSA-N
Biochem/physiol Actions
Anti Trypanosoma, Leishmania agent.
Fexinidazole is a potent anti-Trypanosoma agent. Trypanosoma species human protozoan pathogens are responsible for sleeping sickness and Chagas disease. In vivo, fexinidazole is oxidized to sulfoxide and sulfone metabolites that are effective in blocking the progression of the parasitic disease visceral leishmaniasis. The mechanism of action appears to be by reductive activation via an NADH-dependent nitroreductase expressed by the parasites.
1 of 1
This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description InSolution, 100 mg/mL in DMSO, Suitable for cell culture | description from microbial, ≥94% (TLC) | description ≥98% (HPLC) |
| form powder | form solution | form powder | form powder |
| assay ≥98% (HPLC) | assay - | assay ≥94% (TLC) | assay ≥98% (HPLC) |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: 2 mg/mL, clear | solubility DMSO: soluble | solubility ethanol: soluble, clear to hazy | solubility H2O: 20 mg/mL, clear |
| color light yellow to dark brown | color - | color white to off-white | color white to beige |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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