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SML2383

Isosilybin

≥98% (HPLC)

Synonym(s):

Isosilybin, mixture of isomers, (2R,3R)-2-[2,3-Dihydro-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one, Isosilybinin

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Size/SKUAvailabilityPrice
5 mg
Please contact Customer Service for Availability
3 130,00 CZK
2 660,50 CZK
25 mg
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10 100,00 CZK
8 585,00 CZK

About This Item

Empirical Formula (Hill Notation):
C25H22O10
CAS Number:
Molecular Weight:
482.44
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

2 660,50 CZK

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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

O1C(C(Oc3c1cc(cc3)C4Oc5c(c(cc(c5)O)O)C(=O)C4O)c2cc(c(cc2)O)OC)CO

InChI

1S/C25H22O10/c1-32-17-6-11(2-4-14(17)28)24-20(10-26)33-18-7-12(3-5-16(18)34-24)25-23(31)22(30)21-15(29)8-13(27)9-19(21)35-25/h2-9,20,23-29,31H,10H2,1H3

InChI key

FDQAOULAVFHKBX-UHFFFAOYSA-N

Biochem/physiol Actions

Isosilybin is a diastereoisomeric mixture of flavonolignans isosilybin A and isosilybin B isolated from milk thistle (Silybum marianum) that exhibits hepatoprotective activity. Isosilybin potently inhibits Cytochrome P4502C8 (CYP2C8) activity in human liver microsomes. Also Isosilybin is an activator of PPARγ.

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This Item
SML25811612630T4080
description

≥98% (HPLC)

description

Milk Thistle component, ≥95% (HPLC)

description

United States Pharmacopeia (USP) Reference Standard

description

≥98% (HPLC)

form

powder

form

solid

form

-

form

powder

assay

≥98% (HPLC)

assay

≥95% (HPLC)

assay

-

assay

≥98% (HPLC)

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

-

storage temp.

room temp

solubility

DMSO: 2 mg/mL, clear

solubility

ethanol: 5 mg/mL

solubility

-

solubility

DMSO: >5 mg/mL

color

white to beige

color

-

color

-

color

yellow


Pictograms

Exclamation mark

Signal Word

Warning

Hazard Codes

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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