Skip to Content
Merck

SML2295

Dimethyoxy-etomidate

≥98% (HPLC)

Synonym(s):

(R)-ethyl 1-(1-(3,5-dimethoxyphenyl)ethyl)-1H-imidazole-5-carboxylate

Slide 1 of 1
Sign In to View Organizational & Contract Pricing.

About This Item

Empirical Formula (Hill Notation):
C16H20N2O4
CAS Number:
2300142-82-7
Molecular Weight:
304.34
UNSPSC Code:
12352200
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
oil

Key Documents

View All Documentation

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

assay

≥98% (HPLC)

form

oil

color

colorless to light brown

storage temp.

2-8°C

SMILES string

C[C@@H](N1C=NC=C1C(OCC)=O)C2=CC(OC)=CC(OC)=C2

InChI

1S/C16H20N2O4/c1-5-22-16(19)15-9-17-10-18(15)11(2)12-6-13(20-3)8-14(7-12)21-4/h6-11H,5H2,1-4H3/t11-/m1/s1

InChI key

JETTTZITBCWAQX-LLVKDONJSA-N

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
M7945SML2560SML1280
Dimethyoxy-etomidate ≥98% (HPLC)

Sigma-Aldrich

SML2295

Dimethyoxy-etomidate

Mephetyl tetrazole ≥98% (HPLC), oil

Sigma-Aldrich

M7945

Mephetyl tetrazole

OB-1 ≥98% (HPLC)

Sigma-Aldrich

SML2560

OB-1

TT01001 ≥98% (HPLC)

Sigma-Aldrich

SML1280

TT01001

form

oil

form

oil

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

color

colorless to light brown

color

pale yellow

color

white to very dark brown

color

white to beige

Biochem/physiol Actions

Dimethyoxy-etomidate is a potent suppressor of adrenocortical steroid synthesis by inhibiting steroid 11β-hydroxylase. Dimethyoxy-etomidate is essentially divided of etomidate′s GABAA receptor positive modulatory and sedative-hypnotic activities.
potent suppressor of adrenocortical steroid synthesis, selective inhibitor of steroid 11β-hydroxylase
Dimethyoxy-etomidate is a phenyl ring substituted etomidate analog.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000056735
0000056734
0000040036

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Behavioral and steroidogenic pharmacology of phenyl ring substituted etomidate analogs in rats
McGrath M, et al.
BMC Pharmacology & Toxicology, 20, 1-9 (2019)
Megan McGrath et al.
The Journal of pharmacology and experimental therapeutics, 364(2), 229-237 (2017-12-06)
Cushing's syndrome is characterized by the overproduction of adrenocortical steroids. Steroidogenesis inhibitors are mainstays of medical therapy for Cushing's syndrome; unfortunately, adverse side effects and treatment failures are common with currently available drugs. The general anesthetic induction agent etomidate is

Global Trade Item Number

SKUGTIN
SML2295-25MG04061835502172
SML2295-5MG04061835502189

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service