SML1894

SYP-5

≥98% (HPLC)

• Synonym(s): (2E)-1-(5-Hydroxy-2-2-dimethyl-2H-1-benzopyran-6-yl)-3-(2-thienyl)-2-propen-1-one, (E)-1-(5-Hydroxy-2,2-dimethyl-2H-chromen-6-yl)-3-(thio-phen-2-yl)prop-2-en-1-one
• Empirical Formula (Hill Notation): C₁₈H₁₆O₃S
• CAS Number: 1384268-04-5
• Molecular Weight: 312.38
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD30534394
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: OC1=C(C=CC(C)(C)O2)C2=CC=C1C(/C=C/C3=CC=CS3)=O
• InChI key: OMVURDVBYIJCOI-FNORWQNLSA-N

Description

Biochem/physiol Actions

SYP-5 is potent and selective inhibitor of HIF-1 activity that decreases HIF-1α and HIF-1β protein levels under hypoxic condition. SYP-5 inhibits tumor cell migration and invasion, as well as tumor angiogenesis.

SYP-5 is potent and selective inhibitor of HIF-1 activity.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable