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SML1828

EMD-87580

≥98% (HPLC)

Synonym(s):

EMD87580, N-[2-methyl-4,5-bis(methylsulfonyl)-benzoyl]-guanidine

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Size/SKUAvailabilityPrice
5 mg
Please contact Customer Service for Availability
3 590,00 CZK
25 mg
Please contact Customer Service for Availability
14 500,00 CZK
12 325,00 CZK

About This Item

Empirical Formula (Hill Notation):
C11H15N3O5S2
CAS Number:
Molecular Weight:
333.38
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

3 590,00 CZK


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

−20°C

SMILES string

NC(NC(C1=CC(S(=O)(C)=O)=C(S(=O)(C)=O)C=C1C)=O)=N

InChI

1S/C11H15N3O5S2/c1-6-4-8(20(2,16)17)9(21(3,18)19)5-7(6)10(15)14-11(12)13/h4-5H,1-3H3,(H4,12,13,14,15)

InChI key

GROMEQPXDKRRIE-UHFFFAOYSA-N

Application

EMD-87580 has been used as a selective and potent sodium-hydrogen antiporter 1 (NHE-1) inhibitor in cardiac ventricular myocytes to test its effect on the hypertrophic response.

Biochem/physiol Actions

EMD-87580 is a selective inhibitor of the Na+/H+ exchanger subtype 1 (NHE-1), also known as the Na+/H+ antiporter. EMD-87580 has shown cardioprotective effects, and has been investigated as a possible treatment for Duchenne′s muscular dystrophy.
Inhibitor of sodium-hydrogen exchanger-1 (NHE-1)

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This Item
G5918SML2981I3159
description

≥98% (HPLC)

description

≥98% (HPLC), solid

description

≥98% (HPLC)

description

≥98% (HPLC), solid

form

powder

form

solid

form

powder

form

solid

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: >20 mg/mL

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: >20 mg/mL

color

white to beige

color

white to light pink

color

white to beige

color

-


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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